2024年9月30日 · A brown tumor, also known as osteitis fibrosa cystica and rarely as osteoclastoma, is one of the manifestations of hyperparathyroidism. It represents a reparative cellular process, rather than a neoplastic process.

The brown tumor is a bone lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism. They are a form of osteitis fibrosa cystica. It is not a neoplasm, but rather simply a mass. It most commonly affects the maxilla and mandible, though any bone may be affected. [1] . Brown tumours are radiolucent on x-ray.

A brown tumor is a benign fibrotic, erosive bony lesion caused by localized, rapid osteoclastic turnover, resulting from hyperparathyroidism. Although brown tumors are one of the most pathognomonic signs of primary hyperparathyroidism, they are rarely seen in clinical practice.

Brown tumors are rare focal giant-cell lesions that arise as a direct result of the effect of parathyroid hormone (PTH) on bone tissue in some patients with hyperparathyroidism. Browns tumor is a syndrome associated with an increase in PTH levels by …

Brown tumors are osteolytic bone lesions that occur due to hyperparathyroidism, a condition characterized by excessive secretion of parathyroid hormone (PTH). These lesions are not neoplastic but rather reactive, resulting from excessive osteoclastic activity …

2023年4月20日 · Histologic analysis shows a gross brown mass consisting of microfractures, hemorrhage, macrophages with hemosiderin, bone resorption, and peritrabecular fibrosis (1, 3, 4). Diagnosis is based on a combination of clinical, laboratory, radiologic, and histologic findings.

A brown tumor is a bone lesion that results from bony resorption by excess osteoclastic activity, and replacement by fibrous tissue and giant cells. Brown tumor is an uncommon pathognomonic sign of hyperparathyroidism.

Brown tumors are reactive osteolytic lesions caused by hyperparathyroidism. These rare lesions are non-neoplastic processes that result from bone resorption. The purpose of this study was to retrospectively review a 34-year experience with brown tumors in our institution.

2019年7月29日 · We present cases with full clinical and imaging workup in both the acute and chronic setting and scenarios that require exclusion of primary and secondary bone malignancies. Primary hyperparathyroidism from parathyroid adenoma is …

Brown tumors are rarely seen now in the developed world, but when they do occur they consist of clustered giant cells around minimal bone and fibrous cellular stroma. Brown tumors must be differentiated from giant cell tumors, reparative granulomas and aneurysmal bone cysts.