转录因子调控 | Nature子刊BRD9介导的染色质重塑通过负反馈机制 …
2023年5月8日 · 该研究利用 表观多组学 （ChIP-seq + ATAC-seq + RNA-seq）和机理表型实验 探究了BRD9（bromodomain-containing protein 9）在破骨细胞形成机制中的作用。 骨的功能和 …
BRD9 determines the cell fate of hematopoietic stem cells by
2023年12月15日 · Motivated by recent discovery of disrupted expression of BRD9, an essential component of ncBAF, in multiple cancers, including clonal hematopoietic disorders, we …
BRD9 - Wikipedia
Bromodomain-containing protein 9 is a protein that in humans is encoded by the BRD9 gene. [1] BRD9 contains a bromodomain. It is closely related to BRD7. BRD9 is present in some …
BRD9 defines a SWI/SNF sub-complex and constitutes a specific ...
2019年4月23日 · We report that BRD9 (Bromodomain-containing protein 9) is a preferential dependency for SMARCB1 -mutant RT cells lines. Both shRNA-mediated BRD9 knockdown …
BRD9 Gene - GeneCards | BRD9 Protein | BRD9 Antibody
2025年3月28日 · BRD9 (Bromodomain Containing 9) is a Protein Coding gene. Diseases associated with BRD9 include Sarcoma and Rhabdoid Cancer. Gene Ontology (GO) …
BRD9-mediated chromatin remodeling suppresses ... - Nature
2023年3月14日 · Bromodomain-containing protein 9 (BRD9), a component of non-canonical BAF chromatin remodeling complex, has been identified as a critical therapeutic...
通过靶向含溴结构域蛋白 9 (BRD9) 的表观遗传调控：其治疗潜力 …
最近的数据表明，BRD9 在调节细胞生长方面发挥着重要作用，并被认为可以推动宫颈癌、急性髓性白血病等多种恶性疾病的进展。 它在肿瘤发生中的作用表明选择性 BRD9 抑制剂可能在癌 …
Targeting BRD9 for Cancer Treatment: A New Strategy
2020年12月24日 · Bromodomain-containing protein 9 (BRD9) is a newly identified subunit of the non-canonical barrier-to-autointegration factor (ncBAF) complex and a member of the …
BRD9-mediated chromatin remodeling suppresses …
2023年3月14日 · Bromodomain-containing protein 9 (BRD9), a component of non-canonical BAF chromatin remodeling complex, has been identified as a critical therapeutic target in …
65980 - Gene ResultBRD9 bromodomain containing 9 [ (human)]
2025年2月8日 · BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Bromodomain-containing protein 9 is a prognostic biomarker associated with immune …