2023年4月6日 · In situ atomic force microscopy analysis reveals that mouse bone marrow stiffens with age, which correlates with a compromised HSC niche. Taken together, this study …

This manuscript aims to review the current advances regarding bone marrow aspirate products and proposes the “BMA Matrix” as a feasible part of the orthobiologic landscape in …

Hematopoiesis takes place in the bone marrow (BM) where hematopoietic stem cells and multipotent progenitors (HSPC) self-renew and progressively differentiate into lineage-specific, …

2020年9月1日 · A frequently overlooked component of the bone marrow microenvironment is the extracellular matrix, which not only provides a mechanical scaffold, but also serves as a …

2023年8月15日 · Here, we introduce the most comprehensive resource of bone extracellular matrix (ECM) proteins that can be used in research fields such as bone regeneration, …

Megakaryocytes associate with the bone marrow vasculature where they convert their cytoplasm into proplatelets that protrude through the vascular endothelium into the lumen and release …

Here we review the information on the bone marrow distribution of differentiating pre-osteoclasts relative to the position of the mandatory factors for their differentiation as well as relative to …

We cultured MSCs on an ECM made by bone marrow cells to attempt to reconstitute the MSC niche. This ECM promoted replication of mesenchymal progenitors and retention of their …

2025年2月15日 · Decalcified bone matrix (DBM) is potentially an ideal scaffold because of its natural origin and non-toxic degradation. However, its large pore structures, poor mechanical …

1994年6月1日 · The bone marrow microenvironment consists of a multitude of cellular elements which produce soluble or membrane bound cytokines, a variety of extracellular matrix …