2025年3月30日 · BNIP3L (BCL2 Interacting Protein 3 Like) is a Protein Coding gene. Diseases associated with BNIP3L include Pediculus Humanus Capitis Infestation and Mitochondrial Dna …

BNIP3L首先被发现为一种促凋亡的BCL2家族蛋白，可诱导细胞凋亡或坏死；不过最近的研究发现，BNIP3L可通过自噬促进网织红细胞的线粒体消除。 BNIP3与BNIP3L/NIX具有60%的同源 …

2021年12月20日 · BNIP3L promotes mitophagy either via recruiting autophagosomes to target mitochondria or enhancing the formation of autophagosomes. BNIP3L-mediated mitophagy is …

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally induced …

2009年2月20日 · BNIP3 (BCL2 and adenovirus E1B 19-kDa-interacting protein 3) and BNIP3-like (BNIP3L), also known as NIX, are proteins with homology to BCL2 in the BH3 domain, which …

该基因编码的蛋白质属于 Bcl-2 蛋白质家族中的促凋亡亚家族。 编码的蛋白质与 Bcl-2 结合并具有 BH3 结构域。 该蛋白直接靶向线粒体并引起细胞凋亡变化，包括膜电位的丧失和细胞色素 c 的 …

2021年12月20日 · BNIP3L is initially known to clear the mitochondria during the development of reticulocytes. Recent studies indicated it also engages in a variety of physiological and …

2022年4月11日 · Autophagy-mediated mitochondrial degradation plays pivotal roles in both the acquisition and maintenance of pluripotency, but the molecular mechanisms that link …

2020年8月20日 · We determined that BNIP3L/NIX, a mitophagy receptor, was degraded by proteasomes, which led to mitophagy deficiency in both ischemic neurons and brains. BNIP3L …

The most studied mitophagy receptor BCL2/adenovirus E1B 19-kDa-interacting protein 3-like (BNIP3L/NIX) is shown to be important for the programmed removal of healthy mitochondria …