
Bone morphogenetic protein 10 - Wikipedia
Bone morphogenetic protein 10 (BMP10) is a protein that in humans is encoded by the BMP10 gene. [5][6] BMP10 is a polypeptide belonging to the TGF-β superfamily of proteins. [6] . It is a novel protein that, unlike most other BMP's, is likely to …
BMP10 Gene - Bone Morphogenetic Protein 10
2025年3月30日 · BMP10 (Bone Morphogenetic Protein 10) is a Protein Coding gene. Diseases associated with BMP10 include Myostatin-Related Muscle Hypertrophy and Juvenile Polyposis/Hereditary Hemorrhagic Telangiectasia Syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and MIF Mediated Glucocorticoid Regulation.
Animal-Free BMP-10 蛋白, Human (His) | MCE - MCE-生物活性分 …
Animal-Free BMP-10 蛋白, Human (His) 是重组的 无动物源 BMP-10 蛋白,由 E. coli 表达,带有 C-His 标签。 产品推荐用于细胞培养。 无动物成分 (Animal-free) 重组蛋白,即生产过程中不使用或接触任何动物来源的材料和试剂,具有高一致性和稳定性。 * Please select …
Recombinant Human BMP-10 Protein - R&D Systems
Mature human BMP-10 shares 98% amino acid sequence identity with mouse and rat BMP-10 and 49% - 63% with human BMP-9, GDF-5, -6, and -7. BMP-10 is critical for the proper development of the heart but is not expressed until after cardiac patterning or looping are completed (6-8).
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骨形态发生蛋白 10(BMP10)基因 | MCE - MCE-生物活性 ...
骨形态发生蛋白 10: 该基因编码 tgf-β (转化生长因子-β) 蛋白质超家族的分泌配体。 该家族的配体结合各种 TGF-β 受体,导致调节基因表达的 SMAD 家族转录因子的募集和激活。
BMP10 bone morphogenetic protein 10 [ Homo sapiens (human) ]
Title: Bone morphogenetic protein 10: a novel risk marker of ischaemic stroke in patients with atrial fibrillation. Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10.
BMP10 Signaling Promotes the Development of Endocardial
We show that BMP10 signaling plays a pivotal role in the generation of a population that expresses the collection of markers that define the endocardial lineage in vivo and one that shows a high level of transcriptional similarity to primary human fetal endocardium.
27302 - Gene ResultBMP10 bone morphogenetic protein 10
2025年1月4日 · Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth.
骨形态发生蛋白 10 (BMP-10) | 重组蛋白 - MCE-生物活性 ...
bmp-10 对于胚胎心肌细胞增殖至关重要,可防止 cdkn1c/p57kip 过早激活并确保 mef2c 和 nkx2-5 的最佳表达。 作为 AVRL1/ALK1、BMPR1A/ ALK3 和 BMPR1B/ ALK6 的配体,它激活 SMAD1、SMAD5 和 SMAD8,调节关键信号通路。
JAHA:骨形态发生蛋白10-一种预测房颤患者不良结局的新生物标 …
2023年3月19日 · 近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员的目的是评估新型心房特异性生物标志物骨形态发生蛋白10(BMP10)对房颤患者死亡和MACE的预测价值,并与NT-proBNP进行比较。 在参加瑞士心房颤动研究 (Swiss - AF,一项前瞻性多中心队列研究)的房颤患者中测量了BMP10和NT-proBNP水平。 研究人员共纳入了2219例患者 (中位随访4.3年 [四分位数范围为3.9-5.1],平均年龄为73±9岁,73%为男性)。 在多变量Cox比例风险模型 …