Bicyclic structures occur widely, for example in many biologically important molecules like α-thujene and camphor. A bicyclic compound can be carbocyclic (all of the ring atoms are …

Bicyclic compounds are a specific type of polycyclic compounds, classified as compounds that contain more than one ring with at least two common atoms. The common atoms connecting …

2014年8月14日 · In “ bridged bicyclic ” molecules, the two bridgeheads are separated by “bridges” containing at least one carbon. In “ spiro ” fused molecules, the two rings are both joined at the …

2022年4月27日 · Saturated bicycles are becoming ever more important in the design and development of new pharmaceuticals. Here a new strategy for the synthesis of …

2024年7月20日 · In particular, bicyclo [2.1.1]hexanes (BCHs) have been identified as the molecular replacement for benzenes. Here, we present facile access to a variety of BCHs via …

After completing this section, you should be able to draw the structures and construct molecular models of simple polycyclic molecules. Make certain that you can define, and use in context, …

Understanding the intricacies of bicyclic compounds, from their different types to the nomenclature rules that govern them, can significantly deepen your comprehension of organic chemistry as …

In the fused bicyclic compounds, two rings combine by sharing two adjacent atoms. Here, the rings share one covalent bond, connecting the bridgehead atoms. Fused and bridged bicyclic …

Compounds of this type usually are named by attaching the prefix bicyclo to the name of the open-chain hydrocarbon with the same total number of carbon atoms as in the rings. Thus …

Bioisoteric replacements for aromatic rings to improve medicinal properties are in high demand. This work presents a comprehensive analysis of heretofore-inaccessible 1,2-difunctionalized …