Bepridil (trade name Vascor) is an diamine calcium channel blocker once used to treat angina pectoris. It is no longer sold in the United States. It is nonselective. [1] It has been discussed as a possible option in the treatment of atrial fibrillation. [2] It has been implicated in causing ventricular arrhythmia (torsades de pointes).

Bepridil is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti-hypertensive properties. It is not related chemically to other calcium channel blockers such as diltiazem hydrochloride, nifedipine and verapamil hydrochloride. Mechanism of action

Bepridil is prescribed for patients with angina pectoris (heart pain) due to coronary artery disease. Vascor (bepridil hydrochloride) is indicated for the treatment of chronic stable angina (classic effort-associated angina).

2022年8月15日 · VASCOR (bepridil hydrochloride) is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti- hypertensive properties.

Bepridil is a tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl. It has a role as a vasodilator agent, an anti-arrhythmia drug, an antihypertensive agent and a calcium channel blocker.

Bepridil has generally been well-tolerated. Although adverse side effects have been reported in up to 87% of patients, most were mild to moderate in severity. [Ref] Cardiovascular side effects have been uncommon, but potentially serious.

Bepridil is an anti-anginal agent with a novel chemical structure. Its main pharmacological effects are an increase in coronary blood flow, a reduction in myocardial oxygen demand, reduction in cardiac work, primarily by a decrease in after-load and a …

Detailed Bepridil dosage information for adults. Includes dosages for Angina Pectoris Prophylaxis; plus renal, liver and dialysis adjustments.

Bepridil: Calcium Antagonists. Our drug directory offers in-depth details on its uses, side effects, and more. Get the latest medication information and prescription drug insights today!

2025年1月7日 · Bepridil is a calcium channel blocker that has well characterized anti-anginal properties and known but poorly characterized type 1 anti-arrhythmic and anti-hypertensive properties. It is not related chemically to other calcium channel blockers such as diltiazem hydrochloride, nifedipine and verapamil hydrochloride.