Mar 30, 2025 · BCLAF1 (BCL2 Associated Transcription Factor 1) is a Protein Coding gene. Diseases associated with BCLAF1 include Emery-Dreifuss Muscular Dystrophy and Uterine …

Originally identified as a regulator of apoptosis and transcription, B-cell lymphoma-2-associated transcription factor 1 (BCLAF1) has since been shown to be associated with a multitude of …

Bcl-2-associated transcription factor 1 is a Bcl-2 family protein in humans that is encoded by the BCLAF1 gene. [5] [6] [7] This gene encodes a transcriptional repressor that interacts with …

Jan 22, 2016 · Here, we reveal Bcl-2-associated transcription factor 1 (Bclaf1) as a novel player in the therapeutic drug doxorubicin-induced senescence (TIS) in multiple cancer cells. Bclaf1 is...

Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1alpha under hypoxia. Study identified Bcl2-associated factor 1 (BCLAF1) as a phosphorylation-dependent SDS22 …

Aug 5, 2014 · These findings identify SRSF10 as a key regulator of BCLAF1 pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells.

Feb 6, 2020 · Here we report Bclaf1 is a direct transcriptional target of HIF-1 and upregulated in multiple cell lines during hypoxia. Importantly, we found Bclaf1 is involved in the stabilization of...

Nov 3, 2024 · Title: BCLAF1-induced HIF-1α accumulation under normoxia enhances PD-L1 treatment resistances via BCLAF1-CUL3 complex. TET2-BCLAF1 transcription repression …

Jun 28, 2018 · New insights from Whole Genome Sequencing: BCLAF1 deletion as a structural variant that predisposes cells towards cellular transformation. Role of BCLAF-1 in PD-L1 …

Originally identified as a regulator of apoptosis and transcription, B-cell lymphoma-2-associated transcription factor 1 (BCLAF1) has since been shown to be associated with a multitude of …