DNA binding drives the association of BRG1/hBRM bromodomains …
2017年7月14日 · BRG1 and BRM, central components of the BAF (mSWI/SNF) chromatin remodelling complex, are critical in chromatin structure regulation. Here, we show that the …
BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling …
2019年11月13日 · BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes …
Remodeling Chromatin Induces Z-DNA Conformation Detected …
2020年10月21日 · Remodeling Chromatin Induces Z-DNA Conformation Detected through Fourier Transform Infrared Spectroscopy. The SWI/SNF complex is a highly conserved chromatin …
The SWI/SNF chromatin remodeling complex helps resolve R-loop ... - Nature
2021年5月13日 · BRG1 is the most frequently mutated Snf2-like ATPase in cancer. In the present study, we have investigated the role of SWI/SNF in genome instability, a hallmark of cancer …
Effects of SWI/SNF complex on DNA damage repair in …
2023年12月1日 · The SWI/SNF complex subunits exhibited varying effects on DNA damage repair. BRM/BRG1 knock-down promoted γH2AX accumulation in heterochromatin through …
The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) …
2021年8月8日 · Bromodomains bind to acetylated lysines on histone N-terminal tails and other proteins. The mutually exclusive ATPases of mSWI/SNF complexes, BRG1 and BRM, contain …
Discovery of Orally Active Inhibitors of Brahma Homolog (BRM ... - PubMed
2018年11月21日 · SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2), also known as Brahma homologue (BRM), is a Snf2 …
Remodeling Chromatin Induces Z-DNA Conformation Detected
2020年11月3日 · The SWI/SNF complex is a highly conserved chromatin remodeling complex and can hydrolyze ATP by its catalytic subunit BRG1 or BRM to reconstruct the chromatin. To …
FTIR光谱检测细胞ATP依赖型染色质重塑诱导Z-DNA构象- X-MOL …
2020年10月31日 · 该联合团队采用siRNA和质粒过表达载体转染细胞，即敲低/过表达HepG2和HeLa细胞中的BRG1/BRM，由此调控了染色质重塑复合物SWI/SNF家族的催化亚 …
BRM: the core ATPase subunit of SWI/SNF chromatin-remodelling …
BRM (BRAHMA) is a core, SWI2/SNF2-type ATPase subunit of SWI/SNF chromatin-remodelling complex (CRC) involved in various important regulatory processes including development. …