About Mutations in the BRIP1 Gene - Memorial Sloan Kettering Cancer Center
2023年7月17日 · A BRIP1 mutation increases your risk for ovarian cancer. A BRIP1 mutation may also increase your risk for breast cancer, but more research is needed for us to better …
BRIP1 - Wikipedia
BRIP1 protein is a DNA helicase that is employed in homologous recombinational repair, and in the response of the cell to DNA replication stress. [11] In part, BRIP1 carries out its function …
BRIP1 Gene Mutations: Risks, Management and Treatment
2025年3月13日 · An inherited BRIP1 mutation may affect your options for fallopian tube and ovarian cancer prevention, detection and treatment. FORCE is here to guide you.
BRIP1 Gene - GeneCards | FANCJ Protein | FANCJ Antibody
2025年3月28日 · BRIP1 (BRCA1 Interacting DNA Helicase 1) is a Protein Coding gene. Diseases associated with BRIP1 include Fanconi Anemia, Complementation Group J and Breast …
BRIP1 loss-of-function mutations confer high risk for familial …
2018年1月24日 · Germline mutations in the BRIP1 gene have been described as conferring a moderate risk for ovarian cancer (OC), while the role of BRIP1 in breast cancer (BC) …
深入了解 BRIP1 在泛癌中的致癌、预后和免疫学 ... - X-MOL
肿瘤和正常组织的 brip1 表达数据从癌症基因组图谱、基因型组织表达和人类蛋白质图谱数据库下载。 进一步分析了 BRIP1 与预后、基因组改变、拷贝数变异 (CNV) 以及泛癌甲基化之间的相 …
BRIP1 Mutation - My Cancer Genome
BRIP1 Mutation is a predictive biomarker for use of olaparib in patients. Of the therapies with BRIP1 Mutation as a predictive biomarker, 1 is FDA-approved and 1 has NCCN guidelines in …
BRIP1基因的功能与作用机制解析 - 八方基因
2024年12月30日 · 本文详细介绍了BRIP1基因的功能、作用机制、信号通路及其与疾病的关系，帮助读者全面理解这一关键基因在生物学中的作用。 BRIP1，全称为BRCA1 interacting DNA …
Cancer Risk Management for People with a BRIP1 Mutation
2025年3月13日 · People with an inherited BRIP1 mutation have an increased risk for cancer. Read about medical options for lowering cancer risk or detecting it early. FORCE is here to …
肿瘤遗传易感基因——乳腺癌篇（三）_细胞系 - 搜狐
2019年8月15日 · BRIP1是一种参与DNA修复的肿瘤抑制因子。BRIP1的双等位基因突变与Fanconi贫血有关，而单等位基因突变与遗传性的乳腺癌易感性有关。Cantor等第一次在两个 …