BRD2 Gene - GeneCards | BRD2 Protein | BRD2 Antibody
Mar 28, 2025 · BRD2 (Bromodomain Containing 2) is a Protein Coding gene. Diseases associated with BRD2 include Nut Midline Carcinoma and Adolescence-Adult Electroclinical …
BRD2 - Wikipedia
Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. BRD2 is part of the Bromodomain and Extra-Terminal motif (BET) protein family that also …
靶向BET蛋白的药物发现——研究进展及新技术 - 知乎
溴结构域（Bromodomain，BRD）是一类进化高度保守、能够识别并结合组蛋白乙酰化赖氨酸残基的蛋白结构域，由大约110个氨基酸形成的四条反相平行的α螺旋 (αZ、αA、αB、αC)和两条疏 …
生命学院季雄课题组揭示BRD2介导RNA聚合酶II转录的功能机理
Jun 25, 2022 · brd2/3/4/t是哺乳动物细胞中bet蛋白家族成员，它们均包含两个保守的溴结构域和一个et结构域，是多种疾病抑制剂的关键靶点。 BRD4通过招募转录延伸因子pTEF-b调控PolII的 …
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional ...
In this study, we report that the BET family members Brd2 and Brd4 exert distinct genomic functions at genes whose transcription they co-regulate during mouse T helper 17 (Th17) cell …
BRD2 compartmentalizes the accessible genome - Nature
Apr 11, 2022 · With chemical–genetic perturbations, super-resolution imaging and Micro-C genomic interaction mapping, we show that the BET family scaffold protein BRD2 has the …
6046 - Gene ResultBRD2 bromodomain containing 2 [ (human)]
Results provide evidence that BRD2 is a positive regulator of epithelial-to-mesenchymal transition in breast cancer cells. the bromodomain protein BRD2 is recruited to DNA double-strand breaks.
Bromodomain and Extraterminal Domain Protein 2 in Multiple …
Jun 1, 2024 · In this review, we provide an overview of the structural and physiologic characteristics of bromodomain (BD) and extraterminal domain (BET) protein 2 (BRD2). …
北大生命学院季雄课题组揭示BRD2介导RNA聚合酶II转录的功能机 …
Jun 27, 2022 · BRD2/3/4/T是哺乳动物细胞中BET蛋白家族成员，它们均包含两个保守的溴结构域和一个ET结构域，是多种疾病抑制剂的关键靶点。 BRD4通过招募转录延伸因子pTEF-b调 …
含溴结构域 2（BRD2）基因 | MCE - MCE-生物活性分子大师
该基因编码属于 BET (溴结构域和额外末端结构域) 蛋白质家族的转录调节因子。 这种蛋白质在有丝分裂过程中与转录复合物和乙酰化染色质结合，并通过其两个溴结构域选择性地结合组蛋白 …