2025年3月30日 · BMP4 (Bone Morphogenetic Protein 4) is a Protein Coding gene. Diseases associated with BMP4 include Microphthalmia, Syndromic 6 and Orofacial Cleft 11. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and MIF Mediated Glucocorticoid Regulation.

2025年2月8日 · Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier. Bone morphogenic protein-4 availability in the cardiac microenvironment controls inflammation and fibrosis in autoimmune myocarditis.

Here we review recent studies on BMP4 signalling in the generation of neurons, astrocytes, and oligodendroglial cells in the CNS. We also discuss putative mechanisms that BMP4 may utilise to influence glial cell development following CNS injury and highlight some questions for further research. 1. Introduction.

2017年1月1日 · Title: BMP4 up-regulated by 630 nm LED irradiation is associated with the amelioration of rheumatoid arthritis. BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.

2012年8月17日 · Bone morphogenetic protein 4 (BMP4) is an extracellular signaling molecule that belongs to the family of bone morphogenetic proteins (BMPs) comprising the largest subfamily of the...

Bone morphogenetic protein 4 (BMP4) is emerging as a promising cytokine for regenerative medicine and tissue engineering. BMP4 has been shown to promote the regeneration of teeth, periodontal tissue, bone, cartilage, the thymus, hair, neurons, nucleus pulposus, and adipose tissue, as well as the for …

2023年4月4日 · Bone morphogenetic protein 4 (BMP4), a member of the transforming growth factor beta (TGF- β) superfamily, has been shown to play a crucial role in developmental processes and in the maintenance of various tissues.

Bone Morphogenetic Protein 4 (BMP4) is a protein involved in lung development, where misexpression can lead to abnormalities such as fewer terminal buds and thickened mesenchyme in the lungs. It is also antagonized by Gremlin 1 (Grem1) and plays a role in various developmental processes.

2024年9月18日 · Here we develop a temporal single-cell model of mouse gastrulation that maps continuous and parallel differentiation in embryonic and extraembryonic lineages. This is matched with a three-way...

HGNC Approved Gene Symbol: BMP4. BMP4 is a vital regulatory molecule that functions throughout development in mesoderm induction, tooth development, limb formation, bone induction, and fracture repair.