2017年7月17日 · Our results showed that downregulation of Rb by BMP-2 was associated with ubiquitin-mediated degradation activated by phosphorylation of Rb via the PI3K/AKT signal …

为了研究bmp-2在乳腺癌干细胞（bcscs）发育中的作用，并进一步阐明其对乳腺癌转移的影响机制，我们使用乳腺癌细胞系和临床样品进行了全面的分子研究。

Breast cancer xenograft models were established to observe effects of BMP-2 on the growth and metastasis of xenograft tumors, and real-time PCR and immunohistochemistry were used to …

2017年7月17日 · BMP-2 was reported to facilitate epithelial-to-mesenchymal transition (EMT) 6 and promote the motility and invasiveness of breast cancer cells in vitro and in mouse …

2018年1月16日 · We observed that rhBMP-2 induced epithelial–mesenchymal transition (EMT) in three breast cancer cell lines (MCF-7, MDA-MB-231, and a mouse breast cancer cell line 4T1) …

2008年3月15日 · Atrioventricular (AV) endocardium transforms into the cushion mesenchyme, the primordia of the valves and membranous septa, through epithelial-mesenchymal …

2017年7月17日 · Bone morphogenetic protein 2 (BMP-2) has been reported to facilitate epithelial-to-mesenchymal transition (EMT) and bone metastasis in breast cancer xenograft models. To …

Our results showed that downregulation of Rb by BMP-2 was associated with ubiquitin-mediated degradation activated by phosphorylation of Rb via the PI3K/AKT signal pathway. In addition, …

We observed that rhBMP-2 induced epithelial–mesenchymal transition (EMT) in three breast cancer cell lines (MCF-7, MDA-MB-231, and a mouse breast cancer cell line 4T1) and …

2015年6月30日 · Here, we investigated the role of BMP-2 in colon cancer stem cell (CSC) development from colon cancer cells. We also determined the effects of BMP-2 on CSC …