BK-VP3 as a new target of cellular immunity in BK virus infection
2011年1月15日 · Results: Our data demonstrate for the first time the antigenic properties of all five evaluated proteins with VP3 as a new important target of cellular immunity. Further, we …
BK Polyomavirus-associated nephropathy - Oxford Academic
2025年1月10日 · BK polyomavirus (BKPyV) is a 40–45 nm non-enveloped, icosahedral, closed circular double stranded DNA virus of ∼5 kb, belonging to the same family of viruses as …
The impact of FDA-cleared molecular solutions for BK …
2025年1月17日 · A unique feature of polyomavirus genomes is their bidirectional promoter, allowing for transcription of early (large and small tumor antigens, LTAg, and sTAg) and late …
Global analysis of modifications of the human BK virus structural ...
2010年6月20日 · The results revealed that BK virus is composed of three structural proteins, VP1, VP2, and VP3 and four cellular histones, H2A, H2B, H3, and H4. The major structural protein, …
BK-VP3 as a New Target of Cellular Immunity in BK Virus Infection - LWW
2011年1月15日 · Our data demonstrate for the first time the antigenic properties of all five evaluated proteins with VP3 as a new important target of cellular immunity. Further, we found …
Identification of Candidate Immunodominant Epitopes and Their …
2024年10月22日 · The aim of this study was to predict candidates of immunodominant epitopes within four BK virus proteins (VP1, VP2, VP3 and LTA) using PBMCs from 44 healthy donors. …
Usefulness of BK virus-specific interferon-γ enzyme-linked …
BK virus (BKV) specific interferon γ enzyme-linked immunospot (ELISPOT) results of healthy controls and kidney transplant recipients (KTRs) in three groups of no viremia, BK viremia, and …
BK Virus-Specific Immunity Kinetics: A Predictor of Recovery From ...
2011年11月1日 · BKV-specific cellular immunity directed to nonstructural small and Large T-antigen, and structural VP1–3 was analyzed in an interferon-γ Elispot assay. BKV-specific IgM …
Cellular immunity in BK polyomavirus associated nephropathy …
2022年3月1日 · Data demonstrate for the first time the antigenic properties especially of VP3 as a new important target for cellular immunity: Our study results suggest an implementation of new …
CD4+ T Cell Immune Response to VP1 and VP3 in BK Virus
The peripheral blood mononuclear cells (PBMCs) were cultivated with overlapping peptide pool containing BKV structural proteins VP1, VP2, and VP3, and regulatory proteins large tumor …