Superficial basal cell carcinoma (BCC) is often misdiagnosed as eczematous dermatitis or guttate psoriasis and is often difficult to distinguish clinically from Bowen disease (squamous cell...

CK1 and CK10 expression has been reported in neoplasms with follicular differentiation (TB and BCC), but they cannot be differentiated, based on these markers, because their expression pattern is nearly identical in these pathologies. In this study, we had one mildly CK1-positive case (BCC), and withal samples were CK10-negative.

2020年9月15日 · BCC is the most common skin cancer malignancy and affects more than 3.3 million people annually in the United States. 1 CSCC is the second most common skin cancer, with up to 400,000 U.S. cases...

2020年12月15日 · BCC, fibroepitheliomatous type (fibroepithelioma of Pinkus) Anastomosing strands and cords of basaloid cells connected to the epidermis Peripheral nuclear palisading with a formation of follicular germ-like structures

Basal cell carcinoma must be differentiated from other common causes of skin lesions, such as squamous cell carcinoma, microcystic adnexal carcinoma, trichoepithelioma/trichoblastoma, and merkel cell carcinoma. The following table summarizes common differential diagnosis for basal cell carcinoma : [1]

2022年1月15日 · DDx: Benign hair follicle - lacks necrosis, core has lower cellular density, surrounding sheath composed of loose connective tissue. Trichoepithelioma - no artefactual cleft, [5] and typically no solar elastosis .

Recent reports have suggested that reactivity with the monoclonal antibody Ber-EP4 is capable of separating histologically similar basal cell and squamous carcinomas, and that the expression of bcl-2 or CD34 antigen is able to distinguish BCC from trichoepithelioma. However, corroborative studies of these contentions are few in number.

Experienced dermoscopists can often diagnose superficial basal cell carcinomas by their typical bluish-pink colour, asymmetrical arborising vessels and focal ulceration. Slight scaling and white areas of regression may also be present.

2017年11月1日 · Basal cell carcinoma (BCC) is the most common malignant neoplasm, with an estimated overall lifetime risk of 30% in the United States. 1,2 Although BCC may cause extensive local tissue destruction if not adequately managed, metastasis is exceedingly rare. 2 The diagnosis of BCC is usually straightforward on the dermatopathology service. However ...

2024年7月11日 · Basal cell carcinoma (BCC) is a keratinocyte cancer and the most common type of skin cancer overall. BCC is caused by genetic mutations within the sonic hedgehog signaling pathway affecting the basal keratinocytes, hair follicles, and eccrine sweat glands. Important risk factors include UV exposure and a history of organ transplantation. Some ...