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Entecavir (ETV; Baraclude) is a novel deoxyguanosine analog with activity against hepatitis B virus (HBV). ETV differs from the other nucleoside/tide reverse transcriptase inhibitors approved for HBV therapy, lamivudine (LVD) and adefovir (ADV), in several ways: ETV is >100-fold more potent against HBV in culture and, at concentrations below 1 ...

Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent nucleos(t)ide analogues (NUCs) recommended as first-line monotherapies for chronic hepatitis B. In Phase III trials, ETV and TDF demonstrated superior efficacy, and comparable safety ...

2016年7月1日 · Entecavir (ETV) is a potent viral replication inhibitor for chronic hepatitis B (CHB) patients. To investigate the efficacy of ETV in Chinese nucleos (t)ide (NA)-experienced CHB patients....

2018年4月19日 · 导读：恩替卡韦（entecavir，ETV）是当前慢性乙型肝炎（chronic hepatitis B，CHB）患者抗病毒治疗的一线药物之一。2005年美国食品与药品管理局（FDA）与中国国家食品药品监督管理局（CFDA）相继批准ETV用于CHB治疗。 1. 恩替卡韦（ETV）的推荐用量？

Results: We included randomized clinical trials (RCTs) and cohorts involving Group A: nucleos(t)ide-naive patients (four RCTs, n = 719 patients), Group B: nucleos(t)ide-resistant patients (four cohorts, n = 196 patients), and Group C: entecavir-treated patients with undetectable hepatitis B virus DNA (two RCTs and two cohorts, n = 297). Group A ...

2021年8月10日 · Aim: Hepatitis B virus (HBV) infection is a major public health concern worldwide. Entecavir (ETV), a first-line nucleos(t)ide analogue (NA) for HBV, has a low risk of resistance. We evaluated the efficacy of ETV monotherapy, ratio of ETV-resistant, and the clinical features of patients with ETV resistance.

2021年9月6日 · Entecavir (ETV) is recommended as a first-line anti-HBV treatment. However, many chronic hepatitis B patients initiate anti-HBV treatment such as lamivudine and telbivudine with low genetic barriers in China, which leads to compensatory mutations and increases the rate of ETV resistance.

2018年12月1日 · 恩替卡韦（entecavir，ETV）是当前慢性乙型肝炎（chronic hepatitis B，CHB）患者抗病毒治疗的一线药物之一。2005年美国食品与药品管理局（FDA）与中国国家食品药品监督管理局（CFDA）相继批准ETV用于CHB治疗。临床上恩替卡韦抗乙肝治疗的应用，你 …