Scientists create the first ever autistic monkeys - BBC News
2016年1月28日 · These are the first monkeys ever to have autism. They were genetically modified by Chinese scientists to carry a gene linked to autism in humans. According to Nature, the …
Autism-like behaviours and germline transmission in transgenic
2016年1月25日 · Here we report that lentivirus-based transgenic cynomolgus monkeys (Macaca fascicularis) expressing human MeCP2 in the brain exhibit autism-like behaviours and show …
Atypical behaviour and connectivity in SHANK3 -mutant macaques
2019年6月12日 · The CRISPR–Cas9-mediated generation of germline-transmissible mutations of SHANK3 in cynomolgus macaques (Macaca fascicularis) forms the basis of a non-human …
Monkeys genetically modified to show autism symptoms
2016年1月25日 · Engineered to have a gene that is related to autism spectrum disorder in people, the monkeys are the most realistic animal model of the condition yet, say their creators. …
Induction of core symptoms of autism spectrum disorder by in …
2021年5月15日 · Here we induced genetic mutations in MECP2, a critical gene linked to Rett syndrome (RTT) and autism spectrum disorders (ASD), in the hippocampus (DG and CA1–4) …
CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads …
2019年2月15日 · We have used clustered regularly interspersed short palindromic repeat/CRISPR-associated nuclease 9 to generate a cynomolgus monkey model by disrupting …
First Monkeys with Autism Created in China - MIT Technology Review
2016年1月25日 · Scientists in China say they used genetic engineering to create monkeys with a version of autism, an achievement that could make it easier to test treatments but that raises …
Single-neuron and genetic correlates of autistic behavior in macaque
We report on a Japanese macaque that spontaneously exhibited autistic traits, namely, impaired social ability as well as restricted and repetitive behaviors, along with our single-neuron and …
Genetically modified monkeys show signs of autism, in …
2016年1月25日 · Researchers from Shanghai have genetically modified macaque monkeys to show signs of autism, a step they hope will help develop therapies for human patients.
Detecting autistic-like traits in a general population of monkeys
2020年10月15日 · Fortunately, there is a subset of rhesus monkeys within the natural population illustrating low-social behavior similar to what is observed in humans with ASD. The trick is …