AURKA Gene - GeneCards | AURKA Protein | AURKA Antibody
2025年3月30日 · AURKA (Aurora Kinase A) is a Protein Coding gene. Diseases associated with AURKA include Colorectal Cancer and Thrombocythemia 1. Among its related pathways are …
Aurora kinase A - Wikipedia
Aurora kinase A also known as serine/threonine-protein kinase 6 is an enzyme that in humans is encoded by the AURKA gene. [5] [6] Aurora A is a member of a family of mitotic …
Targeting AURKA in Cancer: molecular mechanisms and …
2021年1月15日 · Activation of AURKA has been demonstrated to play an important role in a wide range of cancers, and numerous AURKA substrates have been identified. AURKA-mediated …
Aurora kinase A, a synthetic lethal target for precision cancer ...
2021年5月28日 · AURKA is a serine/threonine kinase involved in a number of central biological processes, such as the G2/M transition, mitotic spindle assembly, and DNA replication....
AURKA对肿瘤免疫影响的研究进展 - 国际免疫学杂志
AURKA(aurora kinase A)是Aurora激酶家族成员之一，该家族目前已经发现Aurora A，B和C三个成员 。 AURKA最初在果蝇中被发现，其突变引发中心体分离受到抑制，最终导致单极纺锤体形 …
AURKA- 信号通路|蛋白抗体-华美生物
aurka在细胞有丝分裂过程中发挥重要的调控作用，特别是在中心粒成熟、有丝分裂的起始、双极纺锤体的形成和细胞质分裂等方面。 AURKA的生物学意义主要体现在其对肿瘤细胞增殖、基 …
Targeting AURKA in Cancer: molecular mechanisms and ... - PubMed
2021年1月15日 · Aurora kinase A (AURKA) belongs to the family of serine/threonine kinases, whose activation is necessary for cell division processes via regulation of mitosis. AURKA …
Aurora kinase A/AURKA functionally interacts with the ... - Nature
2023年6月29日 · Under these conditions, the abundance of the multifunctional protein Aurora kinase A/AURKA is specifically lowered. We then demonstrate that AURKA functionally …
The AURKA inhibitor alters the immune microenvironment and
2025年2月10日 · Mechanistically, AURKA elevated B7-H3 expression by promoting epidermal growth factor receptor (EGFR) phosphorylation, which was validated in glioma cell lines and …
在癌症中靶向 AURKA：癌症治疗的分子机制和机会,Molecular …
2021年1月15日 · 极光激酶 a (aurka) 属于丝氨酸/苏氨酸激酶家族，其激活是通过调节有丝分裂进行细胞分裂过程所必需的。 根据 TCGA 数据库，对于多种肿瘤类型，AURKA 在癌症组织中 …