
ATOX1 - Wikipedia
ATOX1 is a copper metallochaperone protein that is encoded by the ATOX1 gene in humans. [5] [6] In mammals, ATOX1 plays a key role in copper homeostasis as it delivers copper from the …
SCI | 铜稳态和铜死亡相关最新研究进展 - 知乎 - 知乎专栏
Dec 19, 2022 · 伴侣抗氧化剂1 (atox1)负责将铜转移到高尔基体反面网络 (tgn) 中的atp7a和atp7b,并促进赖氨酰氧化酶、酪氨酸酶和血浆铜蓝蛋白等铜酶的合成(图 1)。 伴侣蛋 …
ATOX1 Gene - GeneCards | ATOX1 Protein | ATOX1 Antibody
Dec 24, 2024 · ATOX1 (Antioxidant 1 Copper Chaperone) is a Protein Coding gene. Diseases associated with ATOX1 include Menkes Disease and Wilson Disease. Among its related …
抗氧化因子 1 铜伴侣(ATOX1)基因 | MCE - MCE-生物活性 ...
抗氧化因子 1 铜伴侣: 该基因编码一个铜伴侣蛋白,它通过将胞质铜结合并转运到反式高尔基体网络中的 ATP 酶蛋白,以便随后掺入血浆铜蓝蛋白,从而在铜稳态中发挥作用。这种蛋白质还 …
文献解读:Memo1与铜伴侣结合蛋白-Atox1相互作用,结合还原 …
铜伴侣蛋白 Atox1,能够将细胞质中的Cu(I)从铜输入器Ctr1移动到高尔基网络中的 ATP 酶 ATP7A 和 ATP7B,以负载分泌通路中的Cu依赖酶,促进癌细胞的迁移。
铜伴侣抗氧化剂 1:多重作用和潜在的治疗靶点,Journal of …
抗氧化剂 1 (atox1) 是 cu 的伴侣分子,以前被称为人类 atx1 同源物 (hah1),已被发现在维持细胞 cu 稳态、抗氧化应激和转录调节中发挥着不可或缺的作用。
Novel role of antioxidant-1 (Atox1) as a copper-dependent ... - PubMed
Apr 4, 2008 · Transfection of Atox1 fused to the DNA-binding domain of Gal4 demonstrated a copper-dependent transactivation in various cell types, including endothelial and cancer cells. …
The Role of Copper Chaperone Atox1 in Coupling Redox …
Human antioxidant protein 1 (Atox1) is a small cytosolic protein with an essential role in copper homeostasis. Atox1 functions as a copper carrier facilitating copper transfer to the secretory …
The ATOX1 Gene Role in Copper Metabolism and the …
Sep 13, 2023 · The ATOX1 (Antioxidant Protein 1) is a human copper metal chaperone that plays an important role in cellular copper homeostasis. The protein is responsible for cytosolic …
ATOX1 基因在铜代谢和铜诱发疾病发病机制中的作用,Russian …
atox1(抗氧化蛋白 1)是一种人类铜金属伴侣,在细胞铜稳态中发挥重要作用。 该蛋白负责从 CTR1(铜转运蛋白 1)吸收胞质铜,并将铜转运至跨高尔基体网络中的铜泵,再转运至 …