《Type 2 alveolar cells are stem cells in adult lung》，由Christina E. Barkauskas等人撰写，发表在《Journal of Clinical Investigation》上。 文章探讨了肺泡II型细胞（AEC2s）在成人肺中的 …

2019年2月8日 · Alveolar type 2 progenitor cells (AT2) seem closest to clinical translation, specifying the evidence that AT2 may satisfactorily control the immune response to decrease...

2022年11月4日 · 肺泡上皮主要由两种类型的上皮细胞组成：肺泡Ⅰ型（at1）和Ⅱ型（at2）细胞。at2 细胞是较小的立方体细胞，以其合成和分泌肺表面活性剂的功能而闻名。此外，at2 细 …

2020年12月1日 · The revelation of AT2 heterogeneity has brought new insights into the role of AT2 cells in various lung disease settings and potentiates the finding of more therapeutics …

2024年5月9日 · Using dual recombinase-mediated intersectional genetic approaches, Liu et al. find that alveolar stem cells (AT2 cells) are derived from existing AT2 cells, club cells, and …

2020年12月31日 · Alveolar type II cells (AT2) are stem cells of lung epithelium. To study these cells, we developed protocols to isolate primary AT2 and test the effects of potential niche …

2025年3月24日 · Alveolar type II (AT2) cells, the primary stem cell population in the distal lung epithelium, are known to be the most common cell of origin for lung adenocarcinoma (LUAD). …

Alveolar epithelial type II cells (AT2) are a heterogeneous population that have critical secretory and regenerative roles in the alveolus to maintain lung homeostasis.

2024年4月12日 · at2细胞作为肺泡上皮干细胞在肺泡损伤修复中发挥重要作用。因此鉴定和阐明at2肺泡干细胞的再生起源及分子调控机制对肺脏疾病的治疗具有重要意义。

AT2 cells have been shown to synthesize, secrete, and recycle all components of pulmonary surfactant, the biochemically heterogeneous complex composed of primarily lipids and protein, …