2025年3月30日 · AP2S1 (Adaptor Related Protein Complex 2 Subunit Sigma 1) is a Protein Coding gene. Diseases associated with AP2S1 include Hypocalciuric Hypercalcemia, Familial, …

AP-2 complex subunit sigma is a protein that in humans is encoded by the AP2S1 gene. [5] [6] [7] One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is …

两个主要的网格蛋白相关接头复合物之一 AP-2 是与质膜相关的异四聚体。 这个复合体由两条大链、一条中链和一条小链组成。 该基因编码该复合物的小链。 可变剪接导致多个转录本变体。 …

AP2S1 regulates APP degradation through late endosome-lysosome fusion in cells and APP/PS1 mice. Mechanism of p38 MAPK-induced EGFR endocytosis and its crosstalk with ligand …

AP2S1 is the sigma 2 subunit of adaptor protein 2 (AP2) that is essential for endocytosis. In this study, we investigated the potential role of AP2S1 in intracellular processing of amyloid …

AP2S1 is the sigma 2 subunit of adaptor protein 2 (AP2) that is essential for endocytosis. In this study, we investigated the potential role of AP2S1 in intracellular processing of amyloid …

Here we show that missense mutations of AP2 σ subunit (AP2S1) affecting Arg15, which forms key contacts with dileucine-based motifs of CCV cargo proteins, result in familial hypocalciuric …

2024年12月10日 · Clinical resource with information about AP2S1, Familial hypocalciuric hypercalcemia 3, and available tests. There are links to practice guidelines and authoritative …

2021年10月14日 · Functional analysis demonstrated that the AP2S1 mutations decreased the sensitivity of CASR-expressing cells to extracellular calcium and reduced CASR endocytosis, …

AP2S1的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为其中两个主要的网格蛋白相关的适配器配合的，AP-2，是一个与质膜相关联的异四聚体。 该复合物由两 …