Antisedan is an α 2-antagonist that competitively inhibits α 2-adrenergic receptors. It rapidly and reliably reverses the effects of Dexdomitor and Dexdomitor 0.1 within 5-10 minutes after IM injection.

ANTISEDAN is indicated for the reversal of the sedative and analgesic effects of DEXDOMITOR (dexmedetomidine hydrochloride), and DOMITOR (medetomidine hydrochloride) in dogs. ANTISEDAN is administered intramuscularly (IM) for reversal of sedation and analgesia regardless of the route used for DEXDOMITOR or DOMITOR.

Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.

2020年6月18日 · ANTISEDAN is indicated for the reversal of the sedative and analgesic effects of DEXDOMITOR (dexmedetomidine hydrochloride), and DOMITOR (medetomidine hydrochloride) in dogs. ANTISEDAN is administered intramuscularly (IM) for reversal of sedation and analgesia regardless of the route used for DEXDOMITOR or DOMITOR.

2020年6月18日 · ANTISEDAN is indicated for the reversal of the sedative and analgesic effects of DEXDOMITOR (dexmedetomidine hydrochloride), and DOMITOR (medetomidine hydrochloride) in dogs. ANTISEDAN is administered intramuscularly (IM) for reversal of sedation and analgesia regardless of the route used for DEXDOMITOR or DOMITOR.

Antisedan (Atipamezole Hydrochloride) Is a Synthetic Α2-adrenergic Antagonist Which Reverses the Effects of Dexdomitor ® (Dexmedetomidine Hydrochloride).each Ml of Antisedan Contains 5.0 mg Atipamezole Hydrochloride as the Medicinal Ingredient, 1.0 mg Methylparaben as the Preservative, 8.5 mg Sodium Chloride, and Water for Injection.

These effects are reversed by the α 2 -antagonist atipamezole (0.1-0.3 mg/kg IM), which is available in a 5 mg/mL formulation (Antisedan). Dexmedetomidine is approved for use in dogs and cats to facilitate physical examination, minor clinical procedures, and as a …

Atipamezole (Antisedan) is quickly absorbed and is generally administered 15–60 minutes after the medetomidine or dexmedetomidine. The optimal dose of Antisedan, in micrograms per kilogram (mcg/kg), is five times that of the previous medetomidine dose or ten times that of the previous dexmedetomidine dose.

2025年3月2日 · ANTISEDAN is indicated for the reversal of the sedative and analgesic effects of DEXDOMITOR (dexmedetomidine hydrochloride), and DOMITOR (medetomidine hydrochloride) in dogs. ANTISEDAN is administered intramuscularly (IM) for reversal of sedation and analgesia regardless of the route used for DEXDOMITOR or DOMITOR.