Anti-Jo1 is an anti-nuclear antibody. [1] [2] Anti-Jo1 has been associated with inflammatory myopathies such as polymyositis, dermatomyositis and antisynthetase syndrome. [3] [4] It has histidine-tRNA ligase as a target.

In this study we focus on anti-Jo-1 (histidyl-tRNA synthetase). This autoantibody is associated with inflammatory muscle diseases and interstitial lung diseases (ILD). We retrospectively identified a cohort of patients tested for the panel of anti-ENA autoantibodies in our hospital.

Anti-Jo-1 is the most common autoantibody seen in antisynthetase syndrome and is present in an estimated 70-90% of patients with Myositis who have associated Interstitial Lung Disease.

Anti-Jo-1 antibody is a myositis specific autoantibody most commonly found in patients with idiopathic inflammatory myopathies (IIM). This antibody is directed against the histidyl-tRNA synthetase which catalyses the binding of the histidine …

Anti-Jo-1 antibodies are present in approximately 20% to 30% of patients with adult-onset polymyositis syndromes. They are present in >65% of patients with both myositis and interstitial lung disease.

Anti-synthetase antibodies specific to myositis are the defining feature of anti-synthetase syndrome. Anti-histidyl-tRNA synthetase and anti-Jo-1 are the most commonly found anti-synthetase antibodies. Less common antibodies include anti …

Anti-Jo-1 autoantibodies represent essential markers in the diagnosis of antisynthetase syndrome (ASS). In this retrospective study, we aimed to investigate whether their concentrations and fluctuations could both respectively reflect the severity and evolution of ASS.

Anti-Jo-1 antibody is a myositis-specific autoantibody most commonly found in patients with idiopathic inflammatory myopathies (IIM). Presence of Jo-1 (antihistidyl transfer RNA [t-RNA] synthetase) antibody is associated with poly myositis and may also be seen in patients with dermato myositis.

We describe the clinical characteristics of our patients with anti-Jo-1 antibody disease, more than half of whom are AA reflecting the demographics of our medical center. We identified 15 patients with Jo-1 positive antibodies who were seen in our …

2007年4月12日 · The presence of a positive ANA and anti-jo antibody test is very suggestive of polymyositis. However blood tests, no matter how positive, do not make the diagnosis of an autoimmune disease. In general, the diagnosis of any autoimmune inflammatory disease requires the right symptoms and even better, the findng of inflammation on examination and ...