Anti-Fas Antibody
使用该抗Fas抗体（人，活化），克隆CH11检测Fas，已发表，并经验证可用于流式细胞术（FC）、免疫细胞化学（IC）和蛋白质印迹（WB）。 0.5-2 μg/mL先前批次在Raji细胞裂解液中检测到Fas。 5-10 μg/mL的先前批次在用4%福尔马林/2%乙酸固定的HeLa细胞上，检测到Fas。 由独立实验室使用20 μg/mL的抗Fas克隆CH11测试先前批次的Fas（Yonehara, S., 1989; Kobayashi, N., 1990）。 通过证明对表达Fas的人细胞的细胞溶解活性进行了常规评估。 用编码人Fas …
Fas 抗体（Fas Antibody） | MCE - MCE-生物活性分子大师
Fas：由该基因编码的蛋白质是 TNF 受体超家族的成员。 该受体包含一个死亡域。 它已被证明在程序性细胞死亡的生理调节中发挥核心作用，并与免疫系统的各种恶性肿瘤和疾病的发病机制有关。 该受体与其配体的相互作用允许形成诱导死亡的信号复合物，其中包括 Fas 相关死亡结构域蛋白 (FADD)、半胱天冬酶 8 和半胱天冬酶 10。 复合物中半胱天冬酶的自身蛋白水解过程触发下游半胱天冬酶级联，并导致细胞凋亡。 该受体还显示可激活 NF-kappaB、MAPK3/ERK1 和 …
Anti-Fas抗体(ab245450) - Abcam中文官网
ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly. Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adapter proteins. Developed using the ECL technique.
A series of Fas receptor agonist antibodies that demonstrate an …
2012年1月20日 · In this study, phage-display technology was used to identify a human anti-Fas antibody, which could efficiently trigger apoptosis and therefore demonstrate potent in vitro tumour cell-killing ...
Anti-FAS (CD95) Antibodies | Invitrogen
Antibodies that detect FAS (CD95) can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Immunocytochemistry. These antibodies target FAS (CD95) in Human, Mouse, Canine, Rat and Feline samples. Our FAS (CD95) monoclonal,...
Anti-Fas Antibody UPSTATE ® , mouse monoclonal, CH11 | Sigma …
Detect Fas using this Anti-Fas Antibody (human, activating), clone CH11 has been published and validated for use in Flow Cytometry (FC), Immunocytochemistry (IC) and Western Blot (WB).
Fas - Abcam中文官网
Fas (Apo-1/CD95/TNFRSF6) 是一种 1 型跨膜受体，属于肿瘤坏死因子 (TNF) 受体超家族。 该家族成员充当细胞外环境的传感器，并通过多种细胞内因子发出信号，引发相应的细胞反应 1。 从结构上来看，该蛋白的分子量约为 37 kDa，由 335 个氨基酸组成，在各种细胞类型和组织（包括胸腺细胞、活化 T 细胞、肝细胞、心脏和肾脏）中表达 2。 Fas 是一种死亡受体，介导程序性细胞凋亡，以维持免疫稳态。 Fas 与其配体 FasL 之间的相互作用可激活 caspase-8，之后通过下游 …
Anti-Fas抗体(ab82419) - Abcam中文官网
ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly. Contains a death domain involved in the binding of FADD, and maybe to other cytosolic adapter proteins. Milk as blocking agent for 1 hour (s) and 0 minute (s). Concentration: 5% - Temperature: 4°C.
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Apoptotic signalling targets the post-endocytic sorting ... - Nature
2019年7月15日 · Here we report that the endosome associated trafficking regulator 1 (ENTR1), controls cell surface levels of Fas and Fas-mediated apoptotic signalling. ENTR1 regulates, via binding to the...
Anti-fas - Sigma-Aldrich
别名: Anti-FAIM3, Anti-Fas apoptotic inhibitory molecule 3, Anti-Regulator of Fas-induced apoptosis