
Anoikis - Wikipedia
Anoikis is a form of programmed cell death that occurs in anchorage-dependent cells when they detach from the surrounding extracellular matrix (ECM). [1] Usually cells stay close to the …
Anoikis: an emerging hallmark in health and diseases - PubMed
Anoikis is a programmed cell death occurring upon cell detachment from the correct extracellular matrix, thus disrupting integrin ligation. It is a critical mechanism in preventing dysplastic cell …
Anoikis molecular pathways and its role in cancer progression
2013年12月1日 · Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix, behaving as a critical mechanism in preventing adherent-independent cell …
Anoikis | Cell Death & Differentiation - Nature
2005年10月25日 · Apoptosis in response to inappropriate cell/ECM interactions is termed anoikis, a name that in some way implies a special case of cell death initiated by signals not used in...
Anoikis resistance through blebs - Nature Reviews Molecular Cell …
2023年3月14日 · Most cells require attachment to the extracellular matrix (ECM) for survival, and upon detachment undergo a form of apoptotic cell death called anoikis. However, some cells, …
Regulation of anoikis by extrinsic death receptor pathways
2023年9月4日 · Anoikis is a caspase-dependent form of cell death, indicating that cells undergoing anoikis activate caspase family proteinases, triggering a cascade of events leading …
Anoikis - an overview | ScienceDirect Topics
What Is Anoikis? Anoikis is the name given to the induction of apoptosis in cells upon loss of attachment to the extracellular matrix (ECM) and neighboring cells. The relationship between …
Anoikis mechanisms - PubMed
Anoikis is defined as apoptosis that is induced by inadequate or inappropriate cell-matrix interactions. It is involved in a wide diversity of tissue-homeostatic, developmental and …
Anoikis: How the Extracellular Matrix Regulates Life-or ... - Springer
Anoikis is defined broadly as apoptosis that is inhibited by appropriate cell-matrix interactions. Normal and tumor cells vary widely in their sensitivity to anoikis, but, in general, metastatic …
Anoikis - PubMed
Anoikis is apoptosis induced by loss of cell adhesion or inappropriate cell adhesion. Adhesion on the extracellular matrix is important to determine whether a cell is in the correct location and to …