2002年3月1日 · Anisodine | C17H21NO5 | CID 11616712 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2018年11月20日 · Anisodine was separated from the herbal medicine Anisodus tanguticus from Qinghai province, and its hydrobromide form was an originally created new drug in China. It competes with acetylcholine in the M cholinergic receptor to …

Anisodine hydrobromide (Ani) is isolated from the medicinal plant Anisodus tanguticus (Maxim.) Pascher for clinical use. Although considerable research regarding Ani has been reported, the safety profiles of Ani are currently unknown. This study ...

2023年11月14日 · Anisodine, a tropane alkaloid extracted from the root of A. tanguticus, has been used as an ingredient in the compound preparation for treating ischemic stroke in China for more than a decade due to its significant properties of vasoactivity and improvements in microcirculation.

2002年3月1日 · ANISODINE HYDROBROMIDE is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 2 investigational indications. (9-methyl-3-oxa-9-azatricyclo [3.3.1.0 2,4]nonan-7-yl) 2,3-dihydroxy-2-phenylpropanoate.

Anisodine has obvious advantages over conventional therapeutic regime using corticosteroids combined with vasodilators, thrombolytic agents, vitamins, and antibiotics for the treatment of ischemic optic neuropathy.

He et al. used reversed-phase high-performance liquid chromatography (HPLC) to determine the plasma concentrations and pharmacokinetic parameters of anisodamine. The method has a wide linear range with an average of 2.4% intra-day errors and 2.7% inter-day errors.

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2023年5月1日 · Using ornithine and arginine as precursor compounds, putrescine is catalyzed by different enzymes and then undergoes a series of reactions to produce anisodamine.

Like atropine and scopolamine, anisodamine is a non-specific cholinergic antagonist exhibiting the usual spectrum of pharmacological effects of this drug class. It appears to be less potent and less toxic than atropine and displays less CNS toxicity than scopolamine.