Aminosteroids are a group of steroids with a similar structure based on an amino-substituted steroid nucleus. [1] [2] They are neuromuscular blocking agents, acting as competitive …

氨基甾体 （Aminosteroid）是一类结构相似的 甾体，而這些 甾体 的 甾体 核基本上都被 氨基 取代 [1][2]。 氨基甾体是 神经肌肉阻断剂 的成分之一，可以作为 烟碱乙酰胆碱受体 （nAChR）的 …

2004年2月1日 · Less potent non-depolarizing NMBDs have a more rapid onset of action, comparable with succinylcholine. Aminosteroid NMBDs depend on organ function for …

Chemicals called aminosteroids have been shown to help stop cell membrane damage and cell death in animals. The review author searched the medical literature to find out if aminosteroids …

The 21-aminosteroids (lazaroids) (Fig. 3) is a family of compounds that inhibit lipid membrane peroxidation. This goal is achieved by vitamin E-like scavenging of lipid peroxyl radicals. The …

1990年4月1日 · Novel 21-aminosteroids that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma. E. Jon Jacobsen, John M. McCall, Donald E. Ayer, …

Aminosteroid | C19H32ClNO2 | CID 40111 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity …

Acute central nervous system (CNS) injury, eg, ischemia, trauma, results in the almost immediate death of neurons. Surrounding tissue is at risk for further cell death. This circumjacent tissue …

Aminosteroids are a group of nonglucocorticoid steroids that possess antioxidant activity by inhibiting lipid peroxidation, independent of steroid receptor pharmacology. Some clinically …

2001年1月1日 · The realization that the efficacy of methylprednisolone in reducing secondary injury was separate from its hormonal activity stimulated the development of a group of steroid …