Amibegron (SR-58,611A) was a drug developed by Sanofi-Aventis (now Sanofi) which acts as a selective agonist for the β 3 adrenergic receptor. It is the first orally active β 3 agonist developed that is capable of entering the central nervous system , …

Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC 50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity.

2007年11月18日 · Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility. The next evolution of DrugBank is here. Designed for scientists, driven by AI, and powered by real-time insights. This is drug intelligence, redefined. Investigated for use/treatment in depression, irritable bowel syndrome (IBS), and obesity.

阿米贝隆 （英语：Amibegron；开发代号： SR-58,611A）是赛诺菲-安万特（现为 赛诺菲）开发的药物，作为 β 3 肾上腺素受体 （英语：Beta-3 adrenergic receptor） 的选择性 激动剂。 它是第一个开发的 口服 活性β 3 激动剂，能够进入 中枢神经系统 并具有 抗抑郁 和 抗焦虑 作用。 [1][2] 2008年7月31日，赛诺菲-安万特宣布决定停止阿米贝隆的开发。 [3]

Amibegron is an agonist for atypical beta3-adrenoceptors which inhibits intestinal motility. AMIBEGRON is a small molecule drug with a maximum clinical trial phase of III (across all indications) and has 3 investigational indications.

阿米替林，①用于治疗各型抑郁症或抑郁状态。 对内因性抑郁症和更年期抑郁症疗效较好，对反应性抑郁症及神经官能症的抑郁状态亦有效。 对兼有焦虑和抑郁症状的患者，疗效优于丙咪嗪。 与电休克联合使用于重症抑郁症,可减少电休克次数。 ②用于缓解慢性疼痛。 ③亦用于治疗小儿遗尿症、儿童多动症。 N,N-二甲基-3-〔1o，11-二氢-5H-二苯并 [a，d]环庚三烯- 5 - 亚基〕-1-丙胺. C20H23N. 277. 常用其盐酸盐，为无色结晶或白色、类白色粉末；无臭或几乎无臭、味苦，有 …

Amibegron Hydrochloride: 一种β3-adrenergic receptor激动剂药物，由Sanofi (Sanofi)公司最早进行研发，目前全球最高研发状态为终止，作用机制: β3-adrenergic receptor激动剂(β3-肾上腺素能受体激动剂)，治疗领域: 神经系统疾病,其他疾病。

Amibegron Hydrochloride | C22H27Cl2NO4 | CID 121888 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

阿米拜龙是一种药物,它是β3肾上腺素受体的选择性激动剂.它是第一种口服活性β3激动剂,能够进入中枢神经系统,并具有抗抑郁和焦虑作用.

Amibegron is a selective β3-adrenoceptor agonist, with an EC 50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron has anxiolytic and antidepressant activity.