ITGAV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha V undergoes post-translational cleavage …

2025年3月30日 · ITGAV (Integrin Subunit Alpha V) is a Protein Coding gene. Diseases associated with ITGAV include Visceral Myopathy 1 and West Nile Virus. Among its related …

整合素亚基 alpha V： 该基因的产物属于整合素α链家族。 整合素是由一个α亚基和一个β亚基组成的异二聚体整合膜蛋白，在细胞表面粘附和信号传导中发挥作用。

2024年9月11日 · We computationally integrate binding motifs of human integrin alphaV beta6, a skeletal muscle receptor, into a liver-detargeting capsid. Designed AAVs show higher …

2018年1月1日 · Integrin α v is essential for embryonic and perinatal development, with a complete knockout being lethal. Approximately 80% of integrin α v -null mice die between embryonic …

Integrin α v β 3 is highly expressed on activated endothelial cells and new-born vessels, but is absent in resting endothelial cells and most normal organ systems, making it a suitable target …

2025年2月8日 · Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded …

Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is …

Alpha-V integrins comprise a subset sharing a common alpha-V subunit combined with 1 of 5 beta subunits (beta-1, 135630; -3, 173470; -5, 147561; -6, 147558; or -8, 604160). All or most …

2007年1月23日 · The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, …