An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix). The alpha helix is the most common structural arrangement in the secondary structure of proteins .

α-螺旋（Alpha-helix）是蛋白质中最重要的一种局部规则结构形式，其特点是在多肽链中， 每个氨基酸残基的羰基（C=O）和氨基（N-H）基团参与形成氢键。

2023年6月4日 · 在Rosetta中，可以使用make_helix命令生成α-螺旋。该命令需要指定螺旋的起始和结束残基，以及其他相关参数，如螺旋的旋转角度和螺旋的长度。 该命令需要指定螺旋的起始和结束残基，以及其他相关参数，如螺旋的旋转角度和螺旋的长度。

α螺旋（alpha helix (α-helix)；Pauling–Corey–Branson α-helix；3.613-helix）是蛋白质中最常见最典型和含量最丰富的二级结构。 它和 β折叠 因肽段每个二面角Φ和Ψ值都处于同一或几乎同一数值而被称为规正二级结构（C α -N夹角和C α -C夹角）。

An α-helix is a right-handed coil of amino-acid residues on a polypeptide chain, typically ranging between 4 and 40 residues. This coil is held together by hydrogen bonds between the oxygen of C=O on top coil and the hydrogen of N-H on the bottom coil.

The alpha helix is the most common type of helix. They are formed when the carbonyl O of the i th amino acid forms hydrogen bonds to the amide H of the i th +4 aa (4 amino acids away). Figure \(\PageIndex{2}\) shows a short section of an alpha helix running from the N-terminal (bottom) to the C-terminal (top) with the sequence DTASDAA.

2024年9月8日 · α-螺旋（Alpha-helix）是蛋白质中最重要的一种局部规则结构形式，其特点是在多肽链中，每个氨基酸残基的羰基（C=O）和氨基（N-H）基团参与形成氢键。

α helix. A right-handed coiled or spiral conformation. This secondary structure is also sometimes called a classic Pauling-Corey-Branson alpha helix. Among types of local structure in proteins, the α helix is the most regular and the most predictable from …

A common motif in the secondary structure of proteins, the alpha helix (α-helix) is a right-handed coiled conformation, resembling a spring, in which every backbone N-H group donates a hydrogen bond to the backbone C=O group of the amino acid four residues earlier (hydrogen bonding). (See also helix.)

The α helix can be described as a 3.6 13 helix, since the i + 4 spacing adds 3 more atoms to the H-bonded loop compared to the tighter 3 10 helix, and on average, 3.6 amino acids are involved in one ring of α helix. The subscripts refer to the number of atoms (including the hydrogen) in the closed loop formed by the hydrogen bond.