The term N cap (N-cap, Ncap) describes an amino acid in a particular position within a protein or polypeptide. [1] [2] [3] [4] [5] [6] The N cap residue of an alpha helix is the first amino acid …

We have surveyed 393 N-termini of alpha-helices and 156 N-termini of 3(10)-helices in 85 high resolution, non-homologous protein crystal structures for N-cap side-chain rotamer …

2015年2月26日 · They considered two possible models for defining where a helix starts and stops. A model based on φ and ψ angles was rejected. Instead, they chose a model where the …

1994年2月1日 · DNA-induced α-helix capping in conserved linker sequences is a determinant of binding affinity in Cys2-His2 zinc fingers. Journal of Molecular Biology 2000 , 295 (4) , 719-727.

1998年12月24日 · Our objectives were to design, prepare and evaluate the efficieneies of high q-value templates based on almost natural cap sequences and use these to probe, on one …

The regions of the polypeptide chain immediately preceding or following an α-helix are known as Nt- and Ct cappings, respectively. Cappings play a central role stabilizing α-helices due to lack …

2013年7月30日 · Helix-capping motifs are specific patterns of hydrogen bonding and hydrophobic interactions found at or near the ends of helices in both proteins and peptides. In an α-helix, …

1996年1月16日 · The analysis revealed three previously unreported factors that appear to be important for stabilization of an alpha-helix: (a) a second capping box hydrogen bond for the …

The first amino acid of a helix at the N-terminal end is called N-cap and the last amino acid of the helix, at the C-terminal end, is called C- cap. In the N-cap position, uncharged polar amino …

We have determined the N- and C-capping preferences of all 20 amino acids by substituting residue X in the peptides NH2-XAKAAAAKAAAAKAAGY-CONH2 and in Ac …