Aldehyde dehydrogenase (ALDH) is a superfamily of enzymes that detoxify a variety of endogenous and exogenous aldehydes and are required for the biosynthesis of retinoic acid …

Increased expression and activity of ALDH isozymes have been reported in various human cancers and are associated with cancer relapse. As a direct consequence of their significant …

Aldehyde dehydrogenases (ALDH) (EC 1.2.1.3) are a family of nicotinamide adenine dinucleotide (phosphate) (NAD (P)) dependent enzymes, typically with a molecular mass of ca. 50–60 kDa. …

Elevated aldehyde dehydrogenase (ALDH) expression/activity has been identified as an important biomarker of primitive cells in various normal and malignant human tissues. Here we …

2013年12月24日 · Increased aldehyde dehydrogenase (ALDH) activity has been found in murine and human hematopoietic stem cells and human multiple myeloma stem cells...

ALDH activity in cells is generally a combination of the activities of multiple ALDH isoforms. Targeting ALDHs is likely the most direct approach to inhibiting therapy-resistant ALDH …

The aldehyde dehydrogenase (ALDH) is a polymorphic enzyme responsible for the oxidation of aldehydes to carboxylic acids, overexpressed both in normal and cancer stem cells. In this …

2024年3月14日 · In this chapter, it is described how CSCs are detected and isolated by using ALDH activity assay. Aldehyde dehydrogenases (ALDHs) are a family of enzymes that …

High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and various cancer stem cells (CSCs). The ALDEFLUOR system is currently the most commonly …