This strain is congenic on the C57BL/6J genetic background. The Ai14 allele is very similar in design to the Ai9 allele (Stock No. 007909 ) - differing only in the absence (Ai14) or presence …

Ai14小鼠是一种常用于科学研究的基因修饰小鼠品系，类似于Ai9小鼠。 Ai14小鼠携带一个用于报告基因表达的tdTomato红色荧光蛋白基因，该基因被loxP位点夹住的STOP盒子阻断。

Ai14/Cre 或者叫 Cre::Ai14 : Ai14是一个Cre报告等位基因，设计有一个loxP侧翼的STOP盒，防止CAG启动子驱动的红色荧光蛋白变体(tdTomato)的转录。Ai14小鼠在Cre介导的重组后表达稳 …

Enabling Nanoplatforms for Targeted in vivo Delivery of CRISPR/Cas9 Ribonucleoproteins in the Brain. Ai14 mouse has a loxP-flanked STOP cassette preventing transcription of a CAG …

2025年3月29日 · Tissue specimens from Nefh CreERT2/wt;Ai14 +/wt mice (12 females, 6 males, 9–12 weeks old) and Nefh wt/wt;Ai14 +/wt littermate controls (2 females, 9 weeks) were …

Ai品系小鼠：该系列小鼠是一种常用于科学研究的基因修饰小鼠品系，以Ai14小鼠为例：Ai14小鼠携带一个表达tdTomato红色荧光蛋白的基因，该基因被loxP位点夹住的STOP盒子阻断。 这 …

Using previously reported and novel lipid nanoparticle vectors, we deliver mRNA encoding for Cre protein to Ai14 mice, which express tdTomato upon Cre recombination (Figure 1).

1 天前 · The mice used in the study included vGluT2-Cre;Ai14 and vGat-Cre;Ai14 mice, both of which expressed oChIEF-tdtomato, as well as two control groups: Cre mice expressing …

2024年7月2日 · Through serial optimization, ePA-Cre is developed to generate a transgenic mouse line that exhibits 175-fold induction upon illumination. Efficient light-dependent …

常见的有 TdTomato鼠 、 mT/mG鼠 、 LacZ鼠 、彩虹鼠 等，他们的重要作用是对各种特异性表达的Cre工具鼠进行验证，简而言之就是“工具鼠的工具鼠”：前面我们关于 Cre-loxp系统 的介绍 …