Pathology Outlines - Basaloid follicular hamartoma
2019年9月10日 · Cutaneous adnexal neoplasm, morphologically consistent with basaloid follicular hamartoma (see comment) Comment: Basaloid follicular hamartoma demonstrates significant overlap between basal cell carcinoma and has been shown to …
Pathology Outlines - Trichofolliculoma
2023年2月8日 · Skin nonmelanocytic tumor - Trichofolliculoma is a benign adnexal hamartomatous follicular tumor that histologically shows multiple follicles in various stages spreading from a central cystic follicle
Pathology Outlines - Skin nonmelanocytic tumor
Sweat gland derived (apocrine & eccrine glands): adenoid cystic carcinoma (primary cutaneous) cutaneous adnexal NUT carcinoma cutaneous mixed tumor / chondroid syringoma cylindroma digital papillary adenocarcinoma eccrine spiradenoma eccrine syringofibroadenoma endocrine mucin producing sweat gland carcinoma extramammary Paget disease ...
Skin adnexal neoplasms—part 1: An approach to tumours of the ...
In this article, we review the histological features of selected benign, malignant and tumour‐like lesions of pilosebaceous origin (box 1), with emphasis on the diagnostic approach and morphological pitfalls in histological evaluation. Skin appendages are derived from the ectoderm, and start to develop early during the embryological life.
Histopathological Analysis of Skin Adnexal Tumors: A Three Year …
Adnexal tumors (ATs) includes a large spectrum of skin epithelial tumors including hamartoma, hyperplasia, benign, and malignant tumors that originate from or show differentiation toward adnexal epithelial structures, namely, pilosebaceous unit, eccrine, and apocrine.
We reviewed findings in peer-reviewed literature on molecular investigations of cutaneous adnexal tumors published through June 2021. Recent discoveries have revealed diverse oncogenic drivers and tumor suppressor alterations in this class of tumors, implicating pathways including Ras/MAPK, PI3K, YAP/TAZ, beta-catenin, and NF-kappaB.
Molecular pathology of skin adnexal tumours - Plotzke - 2022 ...
Adnexal tumours often present as solitary sporadic lesions, but can herald the presence of an inherited tumour syndrome such as Muir–Torre syndrome, Cowden syndrome or CYLD cutaneous syndrome. In contrast to squamous cell carcinoma and basal cell carcinoma, molecular changes in adnexal neoplasia have been poorly characterised and there are ...
An overview of hair follicle tumours - Diagnostic Histopathology
The main differential diagnoses are microcystic adnexal carcinoma (MAC) and desmoplastic trichoepithelioma (DTE). Some MACs are associated with larger cysts containing laminated keratin, resembling trichoadenoma at first glance; however, MAC is a deeply infiltrative tumour with desmoplasia that shows a substantial proportion of tumour strands ...
Folliculosebaceous cystic hamartoma pathology - DermNet
Folliculosebaceous cystic hamartoma represents a cutaneous biphasic hamartoma. It is composed of epithelial and mesenchymal components in varying proportions, typically occurring in adults in the head and neck area. Several pathogenetic mechanisms underlying this adnexal neoplasm have been proposed. However, there remains much controversy as to ...
Pathology Outlines - Nevus sebaceus of Jadassohn
2023年3月1日 · Nevus sebaceus of Jadassohn (sebaceous nevus , organoid nevus) is considered as a hamartoma, histologically characterized by a complex and abnormal proliferation of epidermis and adnexal structures Menu