ACER2 Gene - GeneCards | ACER2 Protein | ACER2 Antibody
2025年3月30日 · ACER2 (Alkaline Ceramidase 2) is a Protein Coding gene. Diseases associated with ACER2 include Farber Lipogranulomatosis and Spinal Muscular Atrophy With …
碱性神经酰胺酶 2（ACER2）基因 | MCE - MCE-生物活性分子 ...
碱性神经酰胺酶 2： 鞘脂代谢物 1-磷酸鞘氨醇可促进细胞增殖和存活，而其前体鞘氨醇则具有相反的作用。神经酰胺酶 ACER2 水解非常长链的神经酰胺以产生鞘氨醇 (Xu 等人，2006 …
ACER2 - Wikipedia
Alkaline ceramidase 2 also known as ACER2 is a ceramidase enzyme which in humans is encoded by the ACER2 gene. [5] The ACER2/ sphingosine pathway plays an important role in …
Alkaline ceramidase 2 is a novel direct target of p53 and induces ...
2017年3月15日 · In the present study, we have identified ACER2 promoter and also found that ACER2 is a direct transcriptional target gene of p53. Furthermore, we have demonstrated that …
<br>人碱性神经酰胺酶 2 (ACER2) 的底物特异性、膜拓扑结构和活 …
Human alkaline ceramidase 2 (ACER2) plays an important role in cellular responses by regulating the hydrolysis of ceramides in cells. Here we report its biochemical characterization, …
肿瘤抑制因子 p53 通过碱性神经酰胺酶 2 将神经酰胺代谢与 DNA
在此我们证明人类碱性神经酰胺酶 2 (acer2) 是 p53 的新转录靶点，并且 p53 的反式激活介导了 ddr。我们发现 p53 过表达或其通过电离辐射 (ir) 激活会上调细胞中的 acer2。
Cell Death Discov︱吉训明团队揭示慢性低氧是诱导α-突触核蛋白 …
该工作揭示了HIF-2α/Acer2信号通路所介导的神经酰胺代谢和PP2A活力抑制是慢性低氧诱导α-syn病理的关键分子机制（图5）。
碱性神经酰胺酶生化特性、生物学功能及在肝癌中的作用
Alkaline ceramidases (ACERs) are a class of ceramidases (CDase), and three types including ACER1, ACER2, and ACER3 have been identified. ACERs can catalyze the hydrolysis of …
The role of ACER2 in intestinal sphingolipid metabolism and ...
2024年11月22日 · Alkaline ceramidase 2 (ACER2) plays a critical role in sphingolipid metabolism by catalyzing the hydrolysis of ceramide to sphingosine, which is subsequently converted to …
ACER2 alkaline ceramidase 2 [ Homo sapiens (human) ]
Results suggest that the ACER2/sphingosine pathway mediates programmed cell death in response to DNA damage through ROS production. Title: Alkaline ceramidase 2 and its …