
Adenine base editor engineering reduces editing of bystander …
2021年7月1日 · ABE is an effective gene editing tool that can convert an A/T pair to a G/C pair without generating a DNA double-strand break (DSB) or requiring a donor DNA template.
Human cell based directed evolution of adenine base editors …
2021年10月8日 · Here the authors show the generation of a human cell based ABE directional screening system and identification of ABE variant (NG-ABEmax-KR) exhibiting a significant …
A precise and efficient adenine base editor - Cell Press
2022年9月7日 · To reduce the frequent bystander mutations of NG-ABE8e, Gu and his colleagues identified a novel ABE variant (NG-ABE9e) through combinatorial engineering. NG-ABE9e …
Engineering a precise adenine base editor with minimal bystander ...
2022年10月13日 · Through structure-guided engineering, we found ABE8e with an N108Q mutation reduced both adenine and cytosine bystander editing, and introduction of an …
Volume 10, 2021 - Advanced Biomedical Engineering
Advanced Biomedical Engineering (ABE) is an Open Access, peer-reviewed journal covering all topics in biomedical engineering. The official journal of the Japanese Society for Medical and …
The effect of change leadership on employee attitudinal support …
2021年2月22日 · By applying a multidimensional approach to attitude and investigating its hierarchy of effects, this study enhanced our accuracy in explaining the influence change …
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Effective July, 2021
ABE is a non-credit course designed to develop the literacy skills necessary for students to be successful workers, citizens and family members. Students enrolled in the ABE program may …
Multi-Authority ABE, Revisited - IACR Cryptology ePrint Archive
2021年10月15日 · Multi-Authority Attribute-Based Encryption (MA-ABE) is a generalization of ABE where the central authority is distributed across several independent parties. We provide …
Achieving best evidence in criminal proceedings - GOV.UK
2022年1月31日 · Guidance on interviewing victims and witnesses, and guidance on using special measures. Achieving Best Evidence (ABE) was originally published in 2002, when it replaced …
The effect of change leadership on employee attitudinal support …
Onyeneke and Abe (2021) further elaborate that successful change effort is realised through long-term relationships between leaders and followers. The quality of interpersonal relationships,...