ABCD4 Gene - GeneCards | ABCD4 Protein | ABCD4 Antibody
2025年3月28日 · ABCD4 (ATP Binding Cassette Subfamily D Member 4) is a Protein Coding gene. Diseases associated with ABCD4 include Methylmalonic Aciduria And Homocystinuria, …
ABCD4 - Wikipedia
ATP-binding cassette sub-family D member 4 is a protein that in humans is encoded by the ABCD4 gene. [4] [5] [6] The protein encoded by this gene is a member of the superfamily of …
ABCD4 gene - MedlinePlus
The ABCD4 gene provides instructions for making a protein that is involved in the conversion of vitamin B12 (also known as cobalamin) into one of two molecules, adenosylcobalamin …
Translocation of the ABC transporter ABCD4 from the endoplasmic ...
2016年7月26日 · In this study, we show that LMBD1 associates with ABCD4 on the ER membranes and supports the translocation of ABCD4 to lysosomes. We previously reported …
Cryo-EM structure of human lysosomal cobalamin exporter ABCD4
2019年8月29日 · The 606-aa-long human ABCD4 consists of a transmembrane domain (TMD) with six transmembrane (TM) helices followed by a nucleotide-binding domain (NBD).
ABCD4 ATP binding cassette subfamily D member 4 [ (human)]
Results propose a model whereby membrane-bound LMBD1 and ABCD4 facilitate the vectorial delivery of lysosomal vitamin B12 to cytoplasmic MMACHC. mutations altering the putative …
ABCD4基因的意义和作用 - 八方基因 - bafang.org.cn
2024年12月29日 · 本文将详细介绍abcd4基因的意义和作用，包括其位置、功能、相关疾病以及其在遗传学中的重要性。 什么是ABCD4基因？ ABCD4基因，全名为ATP结合盒子亚家族D成 …
Cell Res:中国科大首次解析人类溶酶体维生素B12外排蛋白ABCD4 …
研究表明人类ATP结合盒式（ABC）转运蛋白 ABCD4定位于溶酶体膜上，可能在溶酶体内维生素B12外排至细胞质过程中起到关键作用。 ABCD4基因的突变可能导致一系列先天性维生素B12 …
The lysosomal protein ABCD4 can transport vitamin B
Vitamin B 12 (cobalamin) is an essential micronutrient for human health, and mutation and dysregulation of cobalamin metabolism are associated with serious diseases, such as …
ATP 结合盒亚家族 D 成员 4（ABCD4）基因 | MCE
Ubiquitous expression in small intestine (RPKM 8.4), duodenum (RPKM 8.2) and 25 other tissues. 由该基因编码的蛋白质是 ATP 结合盒 (ABC) 转运蛋白超家族的成员。 ABC 蛋白可跨细胞外 …