ATP7A - Wikipedia
ATP7A, also known as Menkes' protein (MNK), is a copper-transporting P-type ATPase which uses the energy arising from ATP hydrolysis to transport Cu (I) across cell membranes. The …
SCI | 铜稳态和铜死亡相关最新研究进展 - 知乎 - 知乎专栏
2022年12月19日 · Menkes病（又名卷发综合征MD）是一种X连锁隐性疾病，影响铜代谢，由ATP7A基因突变引起。肠道中功能性ATP7A的缺失导致铜向血液中的流出减少、肠细胞中Cu …
ATP7A Gene - GeneCards | ATP7A Protein | ATP7A Antibody
2025年3月30日 · ATP7A (ATPase Copper Transporting Alpha) is a Protein Coding gene. Diseases associated with ATP7A include Menkes Disease and Occipital Horn Syndrome. …
ATP7A-Related Copper Transport Disorders - GeneReviews® - NCBI Bookshelf
2003年5月9日 · Menkes disease, occipital horn syndrome (OHS), and ATP7A-related distal motor neuropathy (DMN) are disorders caused by pathogenic variants in the ATP7A, the X-linked …
ATP7A ATPase copper transporting alpha [ (human)] - National …
2025年2月9日 · ATP7A expression is regulated by retinoic acid receptor beta and it has effects on intracellular copper levels, revealing a link between the anticancer action of retinoids and …
The P-type ATPase transporter ATP7A promotes angiogenesis by ... - Nature
2021年5月25日 · In summary, our study uncovers a novel function of ATP7A to limit autophagy-mediated degradation of VEGFR2, thereby promoting VEGFR2 signaling and angiogenesis, …
ATP 酶铜转运α（ATP7A）基因 | MCE - MCE-生物活性分子大师
该基因编码一种跨膜蛋白，该蛋白在跨膜铜转运中发挥作用。 该蛋白质定位于反式高尔基体网络，预计在该网络中为分泌途径中的铜依赖性酶提供铜。 它在细胞外铜升高的条件下重新定位 …
ATP7A-related copper transport diseases—emerging concepts
2011年1月10日 · Involvement of ATP7A in axonal outgrowth, synapse integrity and neuronal activation underscores the fundamental importance of copper metabolism to neurological …
ATP7A gene - MedlinePlus
The ATP7A gene provides instructions for making a protein that is important for regulating copper levels in the body. Copper is necessary for many cellular functions, but it is toxic when present …
铜离子转运ATP酶α肽（ATP7a）｜ELISA指标 - 百家号
2024年11月15日 · 铜离子转运ATP酶α肽（ATP7a）是一种在生物体内负责铜离子转运的关键蛋白质，ATP7A基因的全称为ATP酶，Cu++转运，α肽（Menkes综合征），位于X染色体 …