
New insights into activation and function of the AMPK
2022年10月31日 · AMP-activated protein kinase (AMPK) is a cellular energy sensor canonically activated by increases in AMP/ADP to ATP ratios.
AMPK: guardian of metabolism and mitochondrial homeostasis
2017年10月4日 · AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even …
AMPK: Benefits, Activators, Side Effects and More - Dr. Axe
2025年1月16日 · Adenosine 5′-monophosphate-activated protein kinase (AMPK) is an enzyme that is known as the body’s “master regulator of energy metabolism.” Why? It works as an …
The AMP-activated protein kinase (AMPK) signaling pathway …
AMPK is a highly conserved sensor of intracellular adenosine nucleotide levels that is activated when even modest decreases in ATP production result in relative increases in AMP or ADP. In …
AMPK: mechanisms of cellular energy sensing and restoration of ...
AMPK is a highly conserved master regulator of metabolism, which restores energy balance during metabolic stress both at the cellular and physiological levels. The identification of …
AMPK activators: mechanisms of action and physiological …
2016年4月1日 · AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with …
Rethinking AMPK: A Reversible Switch Fortifying Cancer Cell …
AMPK signaling in cancer cells in extracellular matrix-attached or matrix-detached states. Cancer cells switch on AMPK signaling in extracellular matrix-attached or -detached conditions …
AMPK: guardian of metabolism and mitochondrial homeostasis
This Review discusses how AMPK functions as a central mediator of the cellular response to energetic stress and mitochondrial insults and coordinates multiple features of autophagy and …
AMPK: restoring metabolic homeostasis over space and time
AMP-activated protein kinase (AMPK) is the primary sensor of cellular energy through adenine nucleotide levels that evolved and is maintained across all eukaryotic organisms. AMPK …
AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs
2015年11月23日 · AMP-activated protein kinase (AMPK) is a key regulator of energy balance expressed ubiquitously in eukaryotic cells. Here we review the canonical adenine nucleotide …
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