Reduction of CD3 or CD1d may lead to dysfunction of T cells by deletion of ABCA7. [8][9] On the other hand, transfected and expressed ABCA7, but not endogenous ABCA7, mediates release …

2025年3月6日 · The human ATP-binding cassette (ABC) transporter ABCA7 participates in the lipidation of apolipoprotein ApoE, a commonly recognized risk factor for Alzheimer’s disease …

2025年3月28日 · ABCA7 (ATP Binding Cassette Subfamily A Member 7) is a Protein Coding gene. Diseases associated with ABCA7 include Alzheimer Disease 9 and Cortical Dysplasia, …

The human ATP-binding cassette (ABC) transporter ABCA7 participates in the lipidation of apolipoprotein ApoE, a commonly recognized risk factor for Alzheimer's disease (AD). How …

ABCA7, a close relative of ABCA1 which facilitates cholesterol efflux to lipid-poor apoproteins, has been implicated in macrophage lipid efflux and clearance of apoptotic cells in in vitro studies. …

Adenosine triphosphate-binding cassette transporter subfamily A member 7 (ABCA7) performs incompletely understood biochemical functions that affect pathogenesis of Alzheimer’s …

2025年1月2日 · ABCA7基因编码的蛋白属于ATP结合盒（ATP binding cassette, ABC）超家族A成员，这个家族的蛋白以能够结合和水解ATP以驱动各种物质的跨膜运输而闻名。 ABCA7 具体 …

2006年4月4日 · In the year 2000, ABCA7, a new member of the A-subfamily, has been identified, and it extended the group of ABC transporters associated with lipid homeostasis. In pioneer …

Structural analysis combined with biochemical assays suggested a lipid transport mechanism of ABCA7. Remarkably, we found the direct interaction between ApoE and ABCA7 and further re …

More recently, analysis based upon ImmGen Deep RNA-seq data showed that Abca7 is one of the most highly expressed ABC transporter in a purified population of mouse immune cells like …