8-OHDG作为内源性及外源性因素对DNA氧化损伤作用的 生物标志物，是一个极有前途的指标，通过8-OHDG的检测可以评估体内氧化损伤和修复的程度，氧化应激与DNA损伤的相互关系，对 …

DNA损伤标志物：8-OHdG作为内源性及外源性因素对DNA氧化损伤作用的生物标志物，是一个极有前途的指标。 通过检测8-OHdG，可以评估体内氧化损伤和修复的程度，以及氧化应激 …

8-OHDG（DNA损伤检测试剂）是由活性氧和氮物质（包括羟基自由基和过氧亚硝酸盐）对 DNA 的氧化损伤产生的关键生物标志物。 荧光法检测和量化氧化DNA损伤 (8-OHdG)直接使用来自 …

In nuclear and mitochondrial DNA, 8-hydroxy-2' -deoxyguanosine (8-OHdG) or 8-oxo-7,8-dihydro-2' -deoxyguanosine (8-oxodG) is one of the predominant forms of free radical-induced …

Reactive oxygen species (ROS) attack guanine bases in DNA easily and form 8-hydroxydeoxyguanosine (8-OHdG), which can bind to thymidine rather than cytosine, based …

2024年7月30日 · To gain insight into the extent of oxidative stress and DNA damage in diabetic kidney disease (DKD), a serious complication of diabetes, we compared the levels of the …

2021年1月1日 · It results in oxidative nuclear and mitochondrial DNA damage, which is implicated in the pathogenesis of a wide variety of diseases. During oxidative stress in mammalian cells, …

2004年1月1日 · Upon DNA repair, 8-OHdG is excreted in the urine. Numerous evidences have indicated that urinary 8-OHdG not only is a biomarker of generalized, cellular oxidative stress …

DNA damage is usually repaired, and the oxidized products are excreted in urine. 8-hydroxy-2-deoxyguanosine is considered a biomarker for oxidative damage of DNA. It is needed to …

2025年3月12日 · Background Mounting evidence suggests that malondialdehyde (MDA) and 8-hydroxy-2’-deoxyguanosine (8-OHdG) are valuable biomarkers of lipid and nucleic acid …