Phospholipase B, also known as lysophospholipase, is an enzyme with a combination of both PLA 1 and PLA 2 activities; that is, it can cleave acyl chains from both the sn -1 and sn -2 positions of a phospholipid. In general, it acts on lysolecithin (which is formed by the action of PLA 2 on lecithin). Phospholipase cleavage sites.

2025年3月30日 · PLBD2 (Phospholipase B Domain Containing 2) is a Protein Coding gene. Diseases associated with PLBD2 include Gallbladder Papillomatosis and Sea-Blue Histiocyte Disease. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is PLBD1. Putative phospholipase. ( PLBL2_HUMAN,Q8NHP8 ) ...

2025年2月18日 · 中性粒细胞是免疫系统中的重要细胞，但由于其寿命短且难以长期培养，研究中常使用细胞系模型来模拟其功能。 以下是常用的人源和动物源中性粒细胞细胞系模型： #### **1. HL-60细胞系 （人源）** - **细胞类型**：人早幼粒细胞白血病细胞。 - **组织来源**：外周血。 - **培养基**：RPMI 1640培养基，含10%胎牛血清（FBS）、1%青霉素/链霉素。 - **培养环境**：37°C、5% CO₂。 - **诱导分化**：可加入1.25% DMSO或1 μM 全反式维甲酸 （ATRA） …

2018年4月1日 · Phospholipases are classified into four major types phospholipase A (PLA1 and PLA 2), phospholipase B (PLB), phospholipase C (PLC), and phospholipase D (PLD) on the basis of cleavage of ester linkage within a phospholipid molecule (Fig. 1).

2025年1月4日 · Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast. Morgan CP, et al. Biochem J, 2004 Sep 1. PMID 15193148, Free PMC Article. The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair. Guard SE, et al. Sci Rep, 2019 Apr 25.

本研究通过PCR手段获得了来源于酿酒酵母的plb2(plb)基因,将其克隆至毕赤酵母表达载体pPIC9K中,成功构建了重组质粒pPIC9K-plb,并将其转化至毕赤酵母GS115中,构建了可表达重组PLB(rPLB)的毕赤酵母工程菌株GS115/pPIC9K-plb。

Phospholipase A1 (PLA 1 ), phospholipase A2 (PLA 2 ), and phospholipase B (PLB) represent acylhydrolases, being able to preferentially cleave the acyl ester bond at the sn-1 acyl chain, the...

2020年2月18日 · Enzymes of the phospholipase superfamily are involved in lipid metabolism, as well as regulation of membrane composition, cell signaling, and inflammation. This review provides an insight into the structure, functional properties, and biotechnological application of phospholipase A2 and phospholipases in general.

Know comprehensive PLBL2 / PLBD2 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.

2024年11月1日 · plb可以通过软件配置实现多种逻辑功能，无需软件参与，大大提高mcu的运行效率。本文旨在全面介绍可编程逻辑单元（plb）的特性和应用，帮助读者快速理解和掌握plb的设计和调试方法。