2024年8月2日 · Ductal - lobular system: Consists of large lactiferous ducts that open to the surface of the nipple via lactiferous sinuses, which branch into ducts and terminal ductules which terminate in acini Acini are grouped together in clusters to form lobules (terminal duct lobular unit) Ductal - lobular system is arranged in series of segments (5 - 10)

2022年6月2日 · LCIS involves the terminal duct lobular unit (TDLU), filling and distending acini > 50% of the acini in a TDLU must be filled and expanded to qualify as LCIS; otherwise, called atypical lobular neoplasia Lobular distention is defined as the presence of ≥ 8 cells in the cross sectional diameter of an acinus

2020年12月7日 · Simple adenosis of the breast is a proliferation of glands with normal 2 cell layer (inner epithelial and outer myoepithelial) configuration involving terminal duct lobular units. It rarely harbors atypia and does not show distortion by fibrosis as seen in other forms of adenosis (e.g. sclerosing, tubular), making diagnosis relatively easy via ...

2025年1月15日 · Involves all acini in a terminal duct lobular unit (TDLU) and so resembles lobular carcinoma in situ but does not distend the acini (i.e. caliber of the involved acini is similar to that of uninvolved acini) Can involve ducts; alteration occurs around the duct as outpouchings producing a cloverleaf pattern Lacks intracytoplasmic mucin

2022年9月14日 · Arises from epithelial (progenitor / stem) cells at the terminal duct lobular unit (as do lobular and other types of breast carcinoma) Although the ductal and lobular nomenclature does not reflect the histogenesis of these tumor types, this terminology remains in common use

2021年8月23日 · Peripheral intraductal papilloma: involves terminal duct lobular unit, usually multiple (papillomatosis) (Arch Pathol Lab Med 2016;140:628) Pathophysiology Poorly understood

2021年11月23日 · Terminal duct lobular units with irregular, variably dilated acini Acini lined by stratified cells (more than 2 cell layers); may form tufts or mounds Lining cells have uniform, ovoid to elongated nuclei that may appear crowded and overlap Apical snouts often present Luminal secretions and calcifications may be present

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2024年1月19日 · The photo depicts duct ectasia. Answer A is incorrect because a history of duct ecstasia does not increase risk for breast carcinoma. Answer B is incorrect because duct ecstasia can be bilateral. Answer D is incorrect because duct ecstasia is most common in perimenopausal and postmenopausal women. Comment Here Reference: Duct ectasia of breast

Answers B and E are incorrect because fibroadenomas and tubular adenomas arise from terminal duct lobular units rather than duct lumens and lack a prominent capsule. They are histogenetically related biphasic lesions, with the stromal component dominating fibroadenoma and florid adenosis-like epithelial proliferation dominating tubular adenoma.