Octreotide, sold under the brand name Sandostatin among others, is an octa peptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was first synthesized in 1979 and binds predominantly to the somatostatin receptors SSTR2 and SSTR5. [5]

Octreotide is a synthetic somatostatin analogue that resembles the native polypeptide in its activity in suppressing levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides.

Octreotide is a peptide drug used to treat acromegaly as well as diarrhea associated with metastatic carcinoid tumors and vasoactive intestinal peptide secreting tumors.

奥曲肽（Octreotide）是人工合成的天然生长抑素的八肽衍生物，其药理作用与生长抑素相似，但作用持续时间更长。 本品具有多种生理活性，如抑制生长激素、促甲状腺素；对胃酸、胰酶、胰高血糖素和胰岛素的分泌有抑制作用；能降低胃的运动和胆囊排空，抑制缩胆囊素-胰酶泌素的分泌，减少胰腺分泌，对胰腺实质细胞膜有直接保护作用；减少内脏血流量，降低门脉压力，减少肠道过度分泌，增加肠道对水和钠的吸收。 用于肢端肥大症。 肝硬化所致食管-胃静脉曲张出血的 …

Octreotide, the first somatostatin analogue introduced for clinical use, inhibits the release of growth hormone, glucagon, and insulin in monkeys 45, 11, and 1.3 times more powerfully,...

Octreotide (SMS 201-995) is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide (SMS 201-995) can bind to the somatostatin receptor and mainly subtypes 2, 3, and 5, increases Gi …

Octreotide is a synthetic octapeptide analog of human somatostatin and is used for the treatment of acromegaly and neuroendocrine tumors. Octreotide decreases splanchnic blood flow and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide, secretin, motilin, and pancreatic polypeptide (Yuhico et al., 2012). Clinically, the ...

The USP Octreotide Peptide family includes: USP Monograph: Octreotide Acetate; API: Octreotide Acetate Reference Standard; System Suitability: Octreotide Non-Cyclic System Suitability Marker Refence Standard; Process-related or degradant impurities: [Lys(Ac)]5-Octreotide Analytical Reference Material ([Acetyl-Lys5]-Octreotide)

Octreotide is a medication used in the management and treatment of acromegaly and thyrotrophinomas. It is in the somatostatin analog class of drugs. This activity describes the indications, action, and contraindications for octreotide as a valuable agent in the management of acromegaly and thyrotrophinomas, as well as carcinoid syndrome.

Octreotide is an FDA-approved peptide drug marketed under the brand name Sandostatin by Novartis Pharmaceuticals. It is an octapeptide somatostatin analog and is primarily employed for treating growth hormone-producing tumors and pituitary tumors.10 It is also used as a radiopharmaceutical.