Progeria is a specific type of progeroid syndrome, also known as Hutchinson–Gilford syndrome or Hutchinson–Gilford progeroid syndrome (HGPS). [8] . A single gene mutation is responsible for causing progeria. The affected gene, known as lamin A (LMNA), makes a protein necessary for holding the cell nucleus together.

2017年9月29日 · Progeria is caused by a genetic mutation. The mutation occurs in the LMNA gene. This gene is responsible for producing a protein that helps maintain the structural integrity of the nucleus...

2024年12月4日 · Progeria, also known as Hutchinson-Gilford progeria syndrome (HGPS), is a rare genetic condition that results in a child's body aging rapidly. A mutation in the LMNA gene causes it to make an...

2021年1月4日 · As with any person suffering from heart disease, children with progeria can experience high blood pressure, strokes, angina (chest pain due to poor blood flow to the heart itself), enlarged heart, and heart failure, all conditions associated with aging.

2015年10月7日 · Researchers examine the involvement of a key mutated protein — progerin — in a premature aging disease in children.

2024年10月1日 · Medically known as Hutchinson-Gilford syndrome, it is sometimes called Benjamin Button disease that refers to the film and fiction ‘The Curious Case of Benjamin Button.’ It is a very rare condition caused by a mutated LMNA gene in your child’s body.

2017年12月19日 · In 2003, a progeria gene was discovered. This has given hope that a cure might one day be found. It is sometimes called “Benjamin Button disease,” after Scott Fitzgerald’s fictional character....

2021年1月28日 · Benjamin button disease is a rare genetic condition in children characterized by early year aging, it has three major types and the most common begin two years after birth; it is not inherited. In patients with Benjamin Button disease, genetic factors increase the risk for developing progressive heart disease from an early age.

2024年11月15日 · On October 5, 2024, the oldest known person with the disease, Sammy Basso, died at the age of 28, according to the Progeria Research Foundation (PRF). An unusual disorder that affects only about 400 individuals around the world at any time, it has been referred to as the “Benjamin Button” disease.

Hutchinson-Gilford progeria syndrome (HGPS), also known as the "Benjamin Button" disease (after the short story and movie "The Curious Case of Benjamin Button"), is another name for progeria. It is a rare genetic disorder that causes a child's body to age quickly.