Upper tract urothelial cancer (UTUC) is a subset of urothelial cancer that is found in the renal pelvis of the ureter. At Johns Hopkins, we have a team of specialist in the Greenberg Bladder Cancer Institute who work together to treat and manage patients with this disease.

The purpose of this guideline is to provide a useful reference on the effective evidence-based diagnoses and management of non-metastatic upper tract urothelial carcinoma (UTUC).

What is Upper Tract Urothelial Carcinoma (UTUC)? Upper Tract Urothelial Carcinoma (UTUC) is a cancer that affects the inside lining (urothelium) of the kidney (the “collecting system” – where urine starts to drain after it is made by the kidney) and the ureter (the tube that carries urine from the kidney to the bladder).

This overview represents the updated European Association of Urology (EAU) Guidelines for the management of upper urinary tract urothelial carcinoma (UTUC).

Between 5% and 10% of all urothelial cancers start in the ureter (or renal pelvis) and are diagnosed as upper tract urothelial carcinoma (UTUC). Typically, 92% of all urothelial carcinomas occur in the bladder, but about 7-8% of urothelial carcinomas occur in …

2024年10月16日 · What is Upper Tract Urothelial Carcinoma (UTUC)? Upper Tract Urothelial Carcinoma, or UTUC, is urothelial carcinoma that occurs in the renal pelvis or ureter (s). Approximately 5-7% of urothelial cancer can occur in the inner lining of the kidney, called the calyx and renal pelvis.

This review paper aims to focus on the epidemiological factors and molecular pathways for UTUC, optimizing surgical management in both low- and high-risk disease, role of perioperative chemotherapy in UTUC and the recent implementation of immune checkpoint therapy in the management of UTUC.

Upper urinary tract urothelial cancer (UTUC) is cancer that starts in the upper urinary tract. This is made up of the ureters and an area of the kidneys called the renal pelvis. UTUC is uncommon. Usually, only one ureter or renal pelvis is affected. UTUC is sometimes called transitional cell carcinoma (TCC).

2025年4月2日 · When UTUC has not progressed outside of the urinary system, surgery is typically the primary treatment. Key Takeaway/A Note from iCliniq: Upper tract urothelial carcinoma (UTUC) is a type of cancer that can develop in the bladder, ureter, urethra, or inner lining of the kidney. Chemotherapy, radiation therapy, and surgery are the major ...

2023年6月1日 · UTUC refers to urothelial tumors that originate from the inner lining of the ureter, calyces, or renal pelvis. 1 Although related in pathogenesis to lower tract (LT) urothelial cancer (bladder and urethra), UTUC is much less common, only affecting 5-10% of all patients with urothelial carcinoma (UC). 2 As a rare disease with complex management ...