
TRAF2 - Wikipedia
7186 22030 Ensembl ENSG00000127191 ENSMUSG00000026942 UniProt Q12933 P39429 RefSeq (mRNA) NM_021138 NM_009422 NM_001290413 RefSeq (protein) NP_066961 …
TNF 受体相关因子 2(TRAF2)基因 | MCE - MCE-生物活性 ...
TNF 受体相关因子 2: 该基因编码的蛋白质是 TNF 受体相关因子 (TRAF) 蛋白质家族的成员。 TRAF 蛋白与 TNF 受体超家族成员结合并介导信号转导。该蛋白直接与 TNF 受体相互作用,并 …
肿瘤坏死因子受体相关因子2 (TRAF2)在TNF信号传导中的作用
2015年7月22日 · 导的分支点.本文主要阐述traf2的分子结构及它的结构与功能的关系,tnf信号传导的分子机制及. traf2在其中的作用,重点关注traf2作为凋亡途径和nf-κb介导的存活途径,即这2条相 …
肿瘤坏死因子受体相关因子(TRAF)信号传递新进展 - 每日生物评论
肿瘤坏死因子受体相关因子(tumor necrosis factor receptor-associated factors, TRAF)是一类重要的具有多功能的细胞内信号转导因子。TRAF参与多种受体家族的信号转导,包括肿瘤坏死因 …
The TRAF2-p62 axis promotes proliferation and survival of
2023年4月20日 · TRAF2 (Tumor necrosis factor receptor-associated factor 2) is a dual function protein, acting as an adaptor protein and a ubiquitin E3 ligase, which plays an essential role in …
The role of TRAF2 in pan-cancer revealed by integrating …
TRAF2 expression in various normal human tissues and its association with diseases. (A) mRNA expression profile of TRAF2 in normal human tissues.(B) Protein expression data of TRAF2 in …
TRAF2 Gene - GeneCards | TRAF2 Protein | TRAF2 Antibody
2025年3月30日 · TRAF2 (TNF Receptor Associated Factor 2) is a Protein Coding gene. Diseases associated with TRAF2 include Myeloma, Multiple and Hematologic Cancer.Among its related …
TNF Receptor Associated Factor 2 (TRAF2) Signaling in Cancer
The most important TRAF2-interacting E3 ligases are cIAP1 and cIAP2. Prominent substrates of the TRAF2-cIAP1/2 complex are kinases, such as transforming growth factor-β (TGF-β) …
Physiological Roles and Mechanisms of Signaling by TRAF2 and …
TRAF2 and TRAF5 are closely related members of the TRAF family of proteins. They are important signal transducers for a wide range of TNF receptor superfamily members, in …
IF 12.067 ‖ 浙大医学院郑敏/赵永超团队揭示TRAF2调控肝癌增殖机 …
2024年1月8日 · 3. TRAF2在体外和体内以p62依赖的方式促进肿瘤生长. 由于p62是TRAF2的底物,作者接下来研究了p62在TRAF2敲除肝癌细胞中的作用机制,发现在TRAF2缺失的细胞 …