RPE65 - Wikipedia
Retinal pigment epithelium-specific 65 kDa protein (also known as RPE65) is a retinoid isomerohydrolase enzyme of the vertebrate visual cycle. [5][6] RPE65 is expressed in the …
眼科知识 | 视网膜色素上皮(RPE)的功能与疾病 - 知乎
视网膜色素上皮 (RPE)是由排列在视网膜最外层的一层规则的多边形细胞组成。 RPE的外侧连接布鲁赫膜和脉络膜，内侧连接光感受器细胞的外节。 外侧呈现出基底内折叠样，这增加了细胞 …
Retinal pigment epithelium 65 kDa protein (RPE65): An update
2022年5月1日 · At the heart of this metabolic pathway is an enzyme known as retinal pigment epithelium 65 kDa protein (RPE65), which catalyzes an unusual, possibly biochemically …
RPE65 Gene - GeneCards | RPE65 Protein | RPE65 Antibody
2024年12月25日 · RPE65 (Retinoid Isomerohydrolase RPE65) is a Protein Coding gene. Diseases associated with RPE65 include Retinitis Pigmentosa 20 and Leber Congenital …
RPE65: Role in the visual cycle, human retinal disease, and gene ...
RPE65 is an isomerohydrolase expressed in retinal pigment epithelium. It is critical for the regeneration of the visual pigment necessary for both rod and cone-mediated vision. Mutations …
关于视网膜色素变性，最全的知识都在这里了 - 知乎
视网膜色素变性，又称 色素性视网膜炎 （Retinitis Pigmentosa， 以下统称RP）是一种遗传性的视网膜疾病，全球患病率大约为1：5000-1：3000。 RP的遗传模式包括 常染色体显性遗传， 常 …
RPE65 gene - MedlinePlus
The RPE65 gene provides instructions for making a protein that is essential for normal vision. The RPE65 protein is produced in a thin layer of cells at the back of the eye called the retinal …
遗传性视网膜色素变性无药可医，中国首个新药尚处临床试验阶段
2022年5月21日 · 国家药监局药品审评中心官网显示，药监局已批准上海朗昇生物自主研发药物lx101注射液用于临床试验，治疗rpe65双等位基因突变相关的遗传性视网膜 ...
视网膜色素上皮 65 kDa 蛋白 (RPE65)：更新,Progress ... - X-MOL
这种代谢途径的核心是一种称为视网膜色素上皮 65 kDa 蛋白 (RPE65) 的酶，它催化一种不寻常的、可能在生物化学上独一无二的反应，该反应由偶联的全反式视黄酯水解和烯烃几何异构化组 …
Retinal Pigment Epithelium 65 kDa Protein (RPE65): An Update
At the heart of this metabolic pathway is an enzyme known as retinal pigment epithelium 65 kDa protein (RPE65), which catalyzes an unusual, possibly biochemically unique, reaction …