Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [2][3] The PP2A heterotrimeric protein phosphatase is ubiquitously …

Protein Phosphatase 2A (PP2A) is an important and ubiquitously expressed serine threonine phosphatase and regulates the function by dephosphorylating many critical cellular molecules …

今日在线的Science论文首次发现 PP2A 这一最重要的磷酸酶可与 Integrator复合物 形成一个全新的转录调控复合物 INTAC 直接调控转录，拓展了转录调控和PP2A相关领域的研究边界。

pp2a ，即 蛋白磷酸酶2 ，是一种酶，在人类中由 ppp2ca 基因编码。是异源三聚体，由催化亚单位c，结构亚单位a和调节亚单位b组成。是丝氨酸苏氨酸磷酸酶，调节 真核细胞 中大部分的磷酸 …

蛋白磷酸酶2A （PP2A）是由支架亚单位A、调节亚单位B和催化亚单位C这三类亚单位不同组合而成的一组磷酸酶，共包含多达60种全酶。 不同的细胞和组织中产生多种功能不同、底物特异 …

2006年12月15日 · Protein Phosphatase 2A (PP2A) plays an essential role in many aspects of cellular physiology. The PP2A holoenzyme consists of a heterodimeric core enzyme, which …

2020年1月8日 · PP2A phosphatase is a key regulator of cell homeostasis and is recurrently inactivated in AML. The anticancer activity of several PP2A-activating drugs (e.g., FTY720) …

2021年12月15日 · Here, we report a mechanism of MMRd and demonstrate that protein phosphatase 2A (PP2A) deletion or inactivation converts cold microsatellite-stable (MSS) into …

2021年7月1日 · PP2A can exist in nearly 100 different subunit combinations in mammalian cells, dictating distinct localizations, substrates and regulatory mechanisms. PP2A is well …

Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that regulates many cellular processes. Given the central role of PP2A in regulating diverse biological functions …