2025年2月19日 · Nearly 90% locoregionally advanced nasopharyngeal carcinoma (LANPC) responds to induction chemotherapy (IC) with significant tumor volume shrinkage. Radiotherapy always follows IC, and reduced volume has been proposed. However, the efficacy and safety of reduced-volume radiotherapy is uncertain.

5 天之前 · Purpose of Review Nasopharyngeal carcinoma (NPC), characterized by its aggressive nature and sensitivity to radiation, demands accurate staging for optimal clinical outcomes. The purpose of this review was to provides a comprehensive overview of the evolution of the TNM staging system for NPC based on recent and previously published studies, with particular …

2025年2月6日 · Nasopharyngeal cancer staging refers to TNM staging of malignant tumors of the nasopharynx. The vast majority of applicable tumors are nasopharyngeal carcinomas, but other epithelial malignancies of the nasopharynx are included, such as minor salivary gland tumors.

3 天之前 · Nasopharyngeal carcinoma (NPC) is an epithelial cancer arising from the nasopharynx epithelium, which is characterized by distinct geographical distribution and highly prevalent in East and Southeast Asia, particularly in South China [].In endemic areas, a combination of genetic, ethnic, and environmental factors is always considered contributory to affect the pathogenesis …

5 天之前 · Introduction. Nasopharyngeal carcinoma (NPC) is an etiologically heterogeneous malignancy originating from the epithelium of the nasopharyngeal mucosa, exhibiting heightened sensitivity to radiation therapy (de Martel et al, 2020).Given the higher susceptibility to tumourigenesis and the restricted access of nasopharynx to surgical treatment due to its …

2025年2月14日 · Nasopharyngeal carcinomas (NPC) are the most common primary malignancy of the nasopharynx. They are of squamous cell origin. Some types are strongly associated with the Epstein-Barr virus (EBV).

5 天之前 · Nasopharyngeal carcinoma (NPC) is a unique type of head and neck cancer with a highly uneven geographical distribution, particularly prevalent in East and Southeast Asia, especially in Southern ...

6 天之前 · Familial aggregation is frequent in nasopharyngeal carcinoma (NPC), but its cause remains unclear. Liao et al. investigate the oral microbiome in NPC family cohorts, revealing strong heritability effects on microbiome and identifying NPC-associated microbes with markedly higher heritability in families exhibiting increased clustering of NPC cases.

6 天之前 · Nasopharyngeal carcinoma (NPC) is an epithelial malignancy originating from the nasopharynx, with an estimated 120,000 new cases worldwide in 2022, 1 and the majority of cases were reported in Southern China and Southeastern Asia. 2 Family aggregation is common in NPC, with about 10% of cases having a family history. 3, 4 Despite significant progress in …

4 天之前 · Introduction. Nasopharyngeal carcinoma (NPC) is a malignant neoplasm arising from the epithelial cells of the nasopharynx. It is particularly prevalent in southern China, Southeast Asia, and North Africa, representing a significant oncological challenge in these regions.